adrenalinen.
/əˈdrɛnəlɪn/, /əˈdrɛnl̩ɪn/, U.S. /əˈdrɛn(ə)lən/ 1. Physiology and Medicine. Originally: an extract of the adrenal glands of animals, supposedly containing a mixture of cortical and medullary hormones (now disused). In later use: spec. a catecholamine which is a naturally occurring hormone and neurotransmitter, mainly synthesized in the adrenal medulla and released in response to stressful situations, and acting especially to increase the rate and strength of the contraction of the heart and constrict blood vessels (thus increasing blood pressure), to dilate bronchi, and to increase the breakdown of glycogen and fat. Also called epinephrine.Chemical name: l-1-(3, 4-dihydroxyphenyl)-2-(methylamino)ethanol; C9H13NO3.Adrenalin is a proprietary name in the United States.Epinephrine is the International Nonproprietary Name (1996) for this compound.
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1893 Guy's Hosp. Gaz. 7 Oct. 317/2 Why should they not, asked Dr. Wilks, be saved by administering adrenals? Every week he looked in the journals to see whether some of his younger colleagues at Guy's had not attempted something in the way of the therapeutics of ‘adrenaline’.
1896 Med. Cent. 4 400/1 Adrenalin.—The extract of the supra-renal capsules, has been used with benefit in Addison's disease, and I have heard privately of a case..in which an attenuation of Adrenalin brought about complete restoration.
1901 J. Takamine in Amer. Jrnl. Pharmacy 73 525 In view of the fact that neither of the authors quoted above have obtained the active principle in a pure form,..I have, therefore, termed my substance, as I isolated, ‘Adrenalin’.
1916 Chem. News 25 Sept. 128/2 Synthetic drugs of all kinds—antipyrine and phenacetin,..piperazine and adrenaline..are produced in large quantities.
1920 Discovery Mar. 88/2 Adrenaline prescribed for Addison's disease.
1949 T. A. Henry Plant Alkaloids (ed. 4) 642 Being more stable to metabolic conditions, ephedrine can be given by mouth, whereas adrenaline has to be used by injection.
1983 L. Thomas Youngest Sci. ii. 13 Adrenalin was there, in small glass ampules, in case he ran into a case of anaphylactic shock.
2003 Irish Daily Mirror 19 July 19/2 If treated quickly enough, anaphylaxis can be reversed with an injection of adrenaline.
2. In non-scientific contexts: excitement, nervous energy; adrenaline identified as a cause of this.
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the mind > emotion > excitement > [noun]
excitation1393
motiona1398
concitation1534
erectiona1586
fermentationc1660
effervescence1744
effervescency1767
intumescence1775
electricity1796
electrization1798
sensation1807
electrification1835
bubblement1842
excitement1846
suscitation1870
exuberation1889
splash1899
rousedness1915
adrenaline1928
drama1930
1928 Oakland (Calif.) Tribune 5 Oct. 51/2 Once the umpire said ‘play ball’ it was like a shot of Adrenalin. The Bambino came out of the ether..by socking out a two-bagger in the very first inning.
1937 Background of War iii. 120 Such inflammatory stuff may get German dander up and German adrenalin flowing but it does not turn brother against brother.
1956 C. P. Snow Homecomings xxxviii. 186 The adrenalin was pumping through her, all pallor had left her and she looked spectacularly well.
1982 P. Benchley Girl of Sea of Cortez vi. 61 She lay there for a second, breathing heavily, then realized—with a surge of adrenaline..that Jobim hadn't followed her.
2007 T. Friend Third Domain v. 161 After boisterous conversation buoyed by adrenaline and vodka, we took a sauna.
Compounds
adrenaline junkie n. originally North American a person who has a compulsive desire for extreme excitement; a thrill-seeker.
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the mind > emotion > excitement > pleasurable excitement > [noun] > thrill of > one seeking
thrill-seeker1928
kickster1963
adrenaline junkie1976
1976 Los Angeles Times 4 Jan. j71/1 For slightly over half his life, he has awakened knowing that he was going to spend the rest of the day falling off horses, rolling cars, totaling motorcycles, hopping off cliffs or being set afire... He admits, ‘I'm an adrenaline junkie.’
1999 Daily Star 23 Apr. 22/3 I like a guy who's a bit of an adrenaline junkie, who'll take me bungee jumping and paragliding.
2006 C. B. Rabe Innovation Killer vii. 117 Adrenaline junkies get their annual fix by whitewater rafting the most treacherous sections of the waterway.
adrenaline rush n. originally North American a physical feeling of intense excitement and stimulation caused by the release of adrenaline; cf. rush n.2 2b.
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the mind > emotion > excitement > [noun] > a state of intense excitement
fireworks1598
transport1658
adrenaline rush1969
1969 Village Voice (N.Y.) 3 July 25/5 A kind of tribal adrenaline rush bolsters all of us; they all take out and check pistols.
1991 Soldier of Fortune Dec. 4/1 Ski racing is right up there with night parachute jumps and firefights for an adrenalin rush.
2006 Cosmo Girl (U.K. ed.) July 4/1 There's nothing like a World Cup match to inspire instant adrenaline-rush excitement.
This entry has been updated (OED Third Edition, December 2011; most recently modified version published online December 2021).
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n.1893