a type of antihistamine drug used in the treatment of allergies
cyproheptadine in American English
(ˌsaiprouˈheptəˌdin)
noun
Pharmacology
a phenothiazine analogue, C21H21N, with antihistaminic action, used in the symptomatic treatment of hay fever and itching
Word origin
[1970–75; cy(clo-) + pro(pyl) + hepta- + (piperi)dine]This word is first recorded in the period 1970–75. Other words that entered Englishat around the same time include: New Age, good old boy, postmodernism, stress test, urban legendhepta- is a combining form meaning “seven,” used in the formation of compound words. Otherwords that use the affix hepta- include: heptachlor, heptamerous, heptastich, heptasyllable, heptavalent
Examples of 'cyproheptadine' in a sentence
cyproheptadine
Using immunological and cell fusion technology, group-specific monoclonal antibodies were produced against cyproheptadine.
Mengyuan Guo, Li Sun, Liqiang Liu, Shanshan Song, Hua Kuang, Gang Cui 2018, 'Ultrasensitive immunochromatographic strip for detection of cyproheptadine', Food and Agricultural Immunologyhttp://dx.doi.org/10.1080/09540105.2018.1490395. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Twenty-three of 24 patients had been treated with amitriptyline, cyproheptadine, orpropranolol.
Kuo-Yu Liao, Fang-Yuan Chang, Li-Te Wu, Tzee-Chung Wu 2011, 'Cyclic Vomiting Syndrome in Taiwanese Children', Journal of the Formosan Medical Associationhttp://www.sciencedirect.com/science/article/pii/S092966461160003X. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
There were no side effects from cyproheptadine in any patient.
Sanjay Prakash, Varsha Patel, Siddharth Kakked, Indravadan Patel, Rahul Yadav 2015, 'Mild serotonin syndrome: A report of 12 cases', Annals of Indian Academy of Neurologyhttp://www.annalsofian.org/article.asp?issn=0972-2327;year=2015;volume=18;issue=2;spage=226;epage=230;aulast=Prakash. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Since her symptoms were well controlled by cyproheptadine, migraine-like attacks were considered.
Tung-Ming Chang, Yu-Yuan Ke, Woan-Ling Chen, Ming Chen, Albert D. Yang 2010, 'Unilateral Agenesis of the Internal Carotid Artery in CHARGE Syndrome', Pediatrics and Neonatologyhttp://www.sciencedirect.com/science/article/pii/S187595721060071X. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
He was started on cognitive behavioral therapy and cyproheptadine and improved gradually.
Shah Aiman, Bharti Kundal, Gurika Chopra 2016, 'Cyclic vomiting syndrome', Saudi Journal of Medicine and Medical Scienceshttp://www.sjmms.net/article.asp?issn=1658-631X;year=2016;volume=4;issue=1;spage=45;epage=46;aulast=Aiman. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Multiple regimens have been proposed including: cyproheptadine, propranolol, amitriptyline, and phenobarbital.
Joyce Saliba, Manoochehr Karjoo, Noha Basouny, Afshin Karjoo, Mirza Beg 2016, 'Single Center Experience with Hydroxyzine in the Treatment of Cyclic Vomiting Syndrome',International Journal of Pediatricshttp://ijp.mums.ac.ir/article_7187_e528a44737c70fb6f2aba475e3c9bc1f.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In detrusor preparations, pyrilamine, fexofenadine and cyproheptadine were effective at inhibiting baseline tension increases in response to histamine.
Zane Stromberga, Russ Chess-Williams, Christian Moro 2019, 'Histamine modulation of urinary bladder urothelium, lamina propria and detrusor contractileactivity via H1 and H2 receptors', Scientific Reportshttp://link.springer.com/article/10.1038/s41598-019-40384-1. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
These results suggest that cyproheptadine may be categorized into antihistamines with little effect on the ventricular repolarization.
Kazuko Kobayashi, Naoki Omuro, Akira Takahara 2014, 'The Conventional Antihistamine Drug Cyproheptadine Lacks QT-interval–Prolonging Actionin Halothane-Anesthetized Guinea Pigs: Comparison With Hydroxyzine', Journal of Pharmacological Scienceshttp://www.sciencedirect.com/science/article/pii/S1347861319302233. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)