(ˌdaɪəˌstɛrɪəʊˈaɪsəmə) or diastereomer (ˌdaɪəˈstɛrɪəmə)
noun
chemistry
a type of isomer that differs in the spatial arrangement of atoms in the molecule, but is not a mirror image; a stereoisomer that is not an enantiomer
Examples of 'diastereoisomer' in a sentence
diastereoisomer
The molecular structure reveals the cis-form as the unique diastereoisomer.
Alexander Briceño, Teresa González, Vladimir V. Kouznetsov, Arnold R. Romero Bohórquez 2010, '2-Ethyl-6-(2-pyridyl)-5,6,6a,11b-tetrahydro-7H-indeno[2,1-c]quinoline', Acta Crystallographica Section Ehttp://scripts.iucr.org/cgi-bin/paper?S1600536810005805. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In the case of the latter, hydrogenation of the styryl products afforded a single diastereoisomer.
Susan Kelleher, Pierre-Yves Quesne, Paul Evans 2009, 'Diastereoselective functionalisation of benzo-annulated bicyclic sultams: Applicationfor the synthesis of cis-2,4-diarylpyrrolidines', Beilstein Journal of Organic Chemistryhttps://doi.org/10.3762/bjoc.5.69. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Alternatively, crystallisation-induced dynamic transformation allows isolation of a single diastereoisomer in up to 85% yield.
Ann Bracegirdle, Jonathan Clayden, Lai Wah Lai 2008, 'Asymmetric synthesis of biaryl atropisomers by dynamic resolution on condensationof biaryl aldehydes with (−)-ephedrine or a proline-derived diamine', Beilstein Journal of Organic Chemistryhttps://doi.org/10.3762/bjoc.4.47. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In some endemic areas, quinidine, a diastereoisomer of the antimalarial quinine, has been employed for replacing the latter.
Carla M. S. MENEZES, Karin KIRCHGATTER, Sílvia Maria DI SANTI, Gilberto A. PAULA,Elizabeth I. FERREIRA 2001, 'In vitro evaluation of quinidine sensitivity in brazilian Plasmodium falciparum isolates:comparative analysis to quinine and chloroquine Avaliação da sensibilidade in vitroà quinidina em isolados brasileiros de Plasmodium falciparum: análise comparativaà quinina e à cloroquina', Revista do Instituto de Medicina Tropical de São Paulohttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652001000400009. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)