a yellow odourless explosive gas, used as a methylating agent. Formula: CH2:N:N
diazomethane in American English
(daiˌæzouˈmeθein, -ˌeizou-)
noun
Chemistry
a yellow, odorless, toxic, explosive gas, CH2N2, used chiefly as a methylating agent and in organic synthesis
Word origin
[diazo- + methane]diazo- is a combining form with the meaning “diazo group,” used in the formation of compoundwords. Other words that use the affix diazo- include: diazo, diazoalkane, diazoamino, diazotype
Examples of 'diazomethane' in a sentence
diazomethane
Petroleum acids were isolated by alkaline extraction and turned into methylesters with diazomethane.
Ćirin-Novta Vera S., Kuhajda Ksenija N., Kevrešan Slavko E., Kandrač Julijan E., RadićLjubica M. 2002, 'Biological activity and structure of natural petroleum acids from Lower oil fractionsof "Velebit" oil', Acta Periodica Technologicahttp://www.doiserbia.nb.rs/img/doi/1450-7188/2002/1450-71880233135C.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Five derivatives of the aldehyde were obtained by diazomethane treatment.
Mário G. de Carvalho, Mário S. R. Gomes, Márcia C. C. de Oliveira, Cleber J. da Silva,Acácio G. de Carvalho 2010, 'Chemical constituents from Piptadenia rigida Benth., Fabaceae, "angico"', Revista Brasileira de Farmacognosiahttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000300007&lng=en&tlng=en. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
This methylation protocol avoids the use of hazardous and high toxic reagents (diazomethane, dimethyl sulfate, methyl iodide).
Maria Cristina Ginnasi, Fernanda Crisante, Roberta Bernini 2011, 'A Convenient and Safe O-Methylation of Flavonoids with Dimethyl Carbonate (DMC)',Moleculeshttp://www.mdpi.com/1420-3049/16/2/1418/. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Reactions of dihetaryl and aryl/hetaryl thioketones with 2-diazopropane, diazoethane, and (trimethylsilyl)diazomethanewere studied at variable temperature.
Grzegorz Mlostoń, Paulina Pipiak, Heinz Heimgartner 2016, 'Diradical reaction mechanisms in [3 + 2]-cycloadditions of hetaryl thioketones withalkyl- or trimethylsilyl-substituted diazomethanes', Beilstein Journal of Organic Chemistryhttps://doi.org/10.3762/bjoc.12.71. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The 5-hydroxy-3,3',4',6,7-pentamethoxy-8-methylflavone derivative was obtained bymethylation with diazomethane.
Branco Alexsandro, Pinto Ângelo C., Ifa Demian R., Braz-Filho Raimundo 2002, 'Two 8C-methylated Flavonols from the Leaves of Vellozia candida Mikan (Velloziaceae)',Journal of the Brazilian Chemical Societyhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532002000300005. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)