a type of glycoside obtained from the foxglove (Digitalis purpurea), used as a cleansing agent
Examples of 'digitonin' in a sentence
digitonin
This effect depends on the concentrations of both digitonin and cholesterol.
Ikhwan Resmala Sudji, Yamunadevi Subburaj, Nataliya Frenkel, Ana J. García-Sáez, MichaelWink 2015, 'Membrane Disintegration Caused by the Steroid Saponin Digitonin Is Related to thePresence of Cholesterol', Moleculeshttp://www.mdpi.com/1420-3049/20/11/19682. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Liver cells were permeabilized with digitonin (20 µg per 1 million cells).
V. M. Merlavsky, R. D. Ostapiv, O. V. Ikkert, V. V. Manko 2015, 'Kinetic parameters of respiration in rat permeabilized hepatocytes upon Са2+ in variousconcentrations in medium and prolonged Influence of taurine', Біологічні студіїhttp://publications.lnu.edu.ua/journals/index.php/biology/article/view/111. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Isolated thylakoid membranes were disrupted by treatment with nonionic detergents digitonin or dodecyl maltoside.
A. V. Semenihin, O. K. Zolotareva 2015, 'Carbonic anhydrase activity of integral-functional complexes of thylakoid membranesof spinach chloroplasts', Ukrainian Biochemical Journalhttp://ukrbiochemjournal.org/wp-content/uploads/2015/07/Semenikhin_3_15.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
At low concentrations, digitonin induces membrane permeability while keeping the membrane intact.
Ikhwan Resmala Sudji, Yamunadevi Subburaj, Nataliya Frenkel, Ana J. García-Sáez, MichaelWink 2015, 'Membrane Disintegration Caused by the Steroid Saponin Digitonin Is Related to thePresence of Cholesterol', Moleculeshttp://www.mdpi.com/1420-3049/20/11/19682. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Mammalian cells were treated with digitonin that selectively permeabilizes the plasma membrane.
Heling Ng, Danielle J Smith, Phillip Nagley 2012, 'Application of flow cytometry to determine differential redistribution of cytochromec and Smac/DIABLO from mitochondria during cell death signaling.', PLoS ONEhttp://europepmc.org/articles/PMC3407092?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In the present investigation we studied the molecular mechanisms of the monodesmosidic saponin digitonin on natural and artificial membranes.
Ikhwan Resmala Sudji, Yamunadevi Subburaj, Nataliya Frenkel, Ana J. García-Sáez, MichaelWink 2015, 'Membrane Disintegration Caused by the Steroid Saponin Digitonin Is Related to thePresence of Cholesterol', Moleculeshttp://www.mdpi.com/1420-3049/20/11/19682. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Digitonin induces membrane permeability or causes membrane rupturing only in the presence of cholesterol in an all-or-none mechanism.
Ikhwan Resmala Sudji, Yamunadevi Subburaj, Nataliya Frenkel, Ana J. García-Sáez, MichaelWink 2015, 'Membrane Disintegration Caused by the Steroid Saponin Digitonin Is Related to thePresence of Cholesterol', Moleculeshttp://www.mdpi.com/1420-3049/20/11/19682. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The dependence of succinate-stimulated respiration on digitonin concentration reached maximum at 20-22 μg of digitonin per 1 million cells.
V. M. Merlavsky, B. O. Manko, O. V. Ikkert, V. V. Manko 2015, 'Experimental substantiation of permeabilized hepatocytes model for investigation ofmitochondria in situ respiration', Ukrainian Biochemical Journalhttp://ukrbiochemjournal.org/wp-content/uploads/2015/12/Merlavsky_6_15.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)