It appears to partition between folded and unstructured states as well as between membrane-bound and aqueously soluble states.
Ulf Dettmer 2018, 'Rationally Designed Variants of α-Synuclein Illuminate Its in vivo Structural Propertiesin Health and Disease', Frontiers in Neurosciencehttps://www.frontiersin.org/article/10.3389/fnins.2018.00623/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)