Three categories of negative health effects were identified: systemic effects, nicotine poisoning, and mechanical injury.
My Hua, Prue Talbot 2016, 'Potential health effects of electronic cigarettes: A systematic review of case reports',Preventive medicine reportshttp://www.sciencedirect.com/science/article/pii/S2211335516300523. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We report a rare and severe form of acute nicotine poisoning secondary to dermal absorption of tobacco.
Manel Weli, Mouna Jerbi, Olfa Chakroun-Walha, Bayen Maalej, Lamia Gargouri, NoureddineRekik, Abdelmajid Mahfoudh 2019, 'An unusual case of pediatric acute nicotine poisoning due to a dermal exposure', Journal of Acute Diseasehttp://www.jadweb.org/article.asp?issn=2221-6189;year=2019;volume=8;issue=1;spage=41;epage=42;aulast=Weli. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
One patient had bradycardia and hypotension which may be related to vagal reaction or acute nicotinepoisoning.
Vikas Thakran, Sivasubramanian Ramakrishnan, Sunil Kumar Verma, Sudhir Shetkar, SandeepSeth, Balram Bhargava 2015, 'Acute effects of chewing tobacco on coronary microcirculation and hemodynamics inhabitual tobacco chewers', Journal of the Practice of Cardiovascular Scienceshttp://www.j-pcs.org/article.asp?issn=2395-5414;year=2015;volume=1;issue=2;spage=138;epage=142;aulast=Thakran. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)