a distempered or disordered condition; disturbance of health, mind, or temper
Word origin
[1525–35; obs. distemperate (dis-1 + temperate) + -ure]This word is first recorded in the period 1525–35. Other words that entered Englishat around the same time include: dominant, folio, inflection, shuffle, signature-ure an abstract-noun suffix of action, result, and instrument, occurring in loanwordsfrom French and Latin. Other words that use the affix -ure include: measure, picture, signature, structure, texture