Association with metabolic traits was evaluated in 736 normoglycaemic, non-obese subjects from a general population.
Marre Michel, Balkau Beverley, Charpentier Guillaume, Bibi Amina, Dechaume Aurélie,Lecoeur Cécile, Cheyssac Claire, Froguel Philippe, Gibson Fernando, Vaxillaire Martine 2006, 'Analysis of common PTPN1 gene variants in type 2 diabetes, obesity and associatedphenotypes in the French population', BMC Medical Geneticshttp://www.biomedcentral.com/1471-2350/7/44. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Ethanol-exposed offspring were normoglycaemic and normoinsulinaemic under basal fasting conditions and had normal pancreatic β-cell mass at postnatal day 30.
Megan E Probyn, Kylie R Parsonson, Emelie M Gårdebjer, Leigh C Ward, Mary E Wlodek,Stephen T Anderson, Karen M Moritz 2013, 'Impact of low dose prenatal ethanol exposure on glucose homeostasis in Sprague-Dawleyrats aged up to eight months.', PLoS ONEhttp://europepmc.org/articles/PMC3606130?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The association between these variants and quantitative traits was also examined in the normoglycaemic adults of the control cohort.
Hercberg Serge, Marre Michel, Tichet Jean, Charpentier Guillaume, Duesing Konsta,Balkau Beverley, Froguel Philippe, Gibson Fernando 2009, 'Evaluating the association of common APOA2 variants with type 2 diabetes',BMC Medical Geneticshttp://www.biomedcentral.com/1471-2350/10/13. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Hyperglycaemic patients admitted to hospital have worse clinical outcomes with higher operational costs than normoglycaemic patients.
Giampietro Beltramello, Valeria Manicardi, Roberto Trevisan 2013, 'Trialogue. Managing hyperglycaemia in internal medicine. Instructions for use: Consensusdocument of the Associazione Medici Diabetologi (AMD), Federazione delle Associazionidei Dirigenti Ospedalieri Internisti (FADOI) and Società Italiana di Diabetologi',Italian Journal of Medicinehttp://www.italjmed.org/index.php/ijm/article/view/74. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)