We describe a rare case of macular vitelliform lesion in association with basal laminar drusen.
Maria Teresa Brizzi Chizzotti Bonanomi, Otacílio de Oliveira Maia Júnior, Leda MineTakei Lower, Yoshitaka Nakashima 2006, 'Descolamento viteliforme macular associado a drusas da lâmina basal: relato de casoVitelliform macular detachment associated with basal laminar drusen: case report',Arquivos Brasileiros de Oftalmologiahttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492006000200025. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
12 color fundus photographs of patients with age-related macular degeneration and drusen were analyzed.
Barbazetto Irene, Sparrow Janet R, Nagasaki Takayuki, Smith R Theodore, Klaver CarolineCW, Chan Jackie K 2003, 'A Method of Drusen Measurement Based on the Geometry of Fundus Reflectance', BioMedical Engineering OnLinehttp://www.biomedical-engineering-online.com/content/2/1/10. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Macular hard drusen were present in 50% of the subjects at the fundus oculi exam.
Marcella Nebbioso, Andrea Barbato, Nicola Pescosolido 2014, 'Scotopic Microperimetry in the Early Diagnosis of Age-Related Macular Degeneration:Preliminary Study', BioMed Research Internationalhttp://dx.doi.org/10.1155/2014/671529. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We herein report on a patient with bilateral optic disc drusen simulating diabetic papillopathy.
Rohan Chawla, Soman Nair, Pradeep Venkatesh, Satpal Garg, Kanhaiya Mittal 2017, 'Bilateral disc drusen in a diabetic patient simulating diabetic papillopathy as acause of disc edema', Indian Journal of Ophthalmologyhttp://www.ijo.in/article.asp?issn=0301-4738;year=2017;volume=65;issue=10;spage=1051;epage=1053;aulast=Chawla. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Multimodal imaging did not reveal any presence of optic disc drusen.
In Hee Moon, Sung Chul Lee, Min Kim 2018, 'Intrapapillary hemorrhage with concurrent peripapillary and vitreous hemorrhage intwo healthy young patients', BMC Ophthalmologyhttp://link.springer.com/article/10.1186/s12886-018-0833-z. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Fundus photography could be helpful to differentiate optic nerve drusen from other ocular conditions.
Pablo Gili, Patricia Flores-Rodríguez, Julio Yangüela, Javier Orduña-Azcona, MaríaDolores Martín-Ríos 2013, 'Evaluation of optic disc size in patients with optic nerve head drusen using fundusphotography', Journal of Optometryhttp://www.sciencedirect.com/science/article/pii/S1888429612000866. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Current manual methods of drusen measurement are laborious and subjective.
Barbazetto Irene, Sparrow Janet R, Nagasaki Takayuki, Smith R Theodore, Klaver CarolineCW, Chan Jackie K 2003, 'A Method of Drusen Measurement Based on the Geometry of Fundus Reflectance', BioMedical Engineering OnLinehttp://www.biomedical-engineering-online.com/content/2/1/10. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
White and yellow spots, which look like drusen in humans, were identified with fundscopic examination.
Hu Huang, Ying Liu, Lei Wang, Wen Li 2017, 'Age-related macular degeneration phenotypes are associated with increased tumor necrosis-alphaand subretinal immune cells in aged Cxcr5 knockout mice.', PLoS ONEhttp://europepmc.org/articles/PMC5345864?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The edges were determined by the detachment of the neuroepithelium and abundance of hard drusen.
Nanuli V Ivanova, Oleg G Rasin, Aleksey V Savchenko, Olga A Litvinenko 2016, 'Switching of an inhibitor of vascular endothelial growth factor in the treatment ofresistant to ranibizumab neovascular form of age-related macular degeneration. Casestudy', Офтальмологические ведомостиhttps://journals.eco-vector.com/ov/article/view/5354. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)