释义 |
oncolysis in British English (ɒŋˈkɒlɪsɪs) nounthe destruction of tumours Examples of 'oncolysis' in a sentenceoncolysis Replication and oncolysis were evaluated in ovarian cancer cells.This review summarizes modifications to reovirus that may improve potency and/or specificity during oncolysis.Surprisingly, only few studies have investigated viral oncolysis in veterinary medicine.Adenoviral gene therapy and oncolysis would critically benefit from targeted cell entry by genetically modified capsids.Viral-mediated oncolysis was determined by tumor growth analysis combined with microscopic studies of intratumoral virus distribution.Because of the important oncolysis of this virus, we developed a novel purifying method for large-scale production.For a long time, the therapeutic efficacy was thought to depend on the direct viral oncolysis (virocentric view).Here we review our current understanding of the mechanism of oncolysis contributing to the broad anticancer activity of reovirus.After death due to the tumor burden, the brains were histopathologically assessed for inflammation and oncolysis. |