a deposit of sodium urate in the helix of the ear or surrounding a joint: a diagnostic of advanced or chronic gout
Also called: chalkstone
Derived forms
tophaceous (təʊˈfeɪʃəs)
adjective
Word origin
C16: from Latin, variant of tōfustufa, tuff
Examples of 'tophi' in a sentence
tophi
Pathologic examination demonstrated typical tophi in the dermis and subcutaneous tissue.
Lu Wang, Crystal Rose, Paul Mellen, George Branam, Maria M. Picken 2014, 'Gouty Panniculitis with Ulcerations in a Patient with Multiple Organ Dysfunctions',Case Reports in Rheumatologyhttp://dx.doi.org/10.1155/2014/320940. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
On the basis of cytological and histopathological findings, a diagnosis of gouty tophi was rendered.
Debashish Bhattacharjee, Santosh K Mondal, Rudra Narayan Ray, Debjani Basu 2017, 'Gouty tophi without hyperuricemia, an interesting case diagnosed by fine-needle aspirationcytology', Egyptian Rheumatology and Rehabilitationhttp://www.err.eg.net/article.asp?issn=1110-161X;year=2017;volume=44;issue=3;spage=139;epage=141;aulast=Bhattacharjee. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Tophi are the visible dermatological signs of gout.
Shyam Verma, Piyush Bhargav, Tushar Toprani, Vishal Shah 2014, 'Multiarticular tophaceous gout with severe joint destruction: A pictorial overviewwith a twist', Indian Journal of Dermatologyhttp://www.e-ijd.org/article.asp?issn=0019-5154;year=2014;volume=59;issue=6;spage=609;epage=611;aulast=Verma. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Tophi are deposits of monosodium crystals in people with long-standing gout.
Jency Maria Koshy, Mary John, Rupinder Kaur, Lydia Solomon 2014, 'Tophi: A pointer towards the diagnosis of gout', CHRISMED Journal of Health and Researchhttp://www.cjhr.org/article.asp?issn=2348-3334;year=2014;volume=1;issue=2;spage=128;epage=129;aulast=Koshy. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The usual manifestations are crystal arthropathy and tophi deposition in the soft tissues.
S. A. Wan, C. L. Teh, A. T. Jobli, Y. K. Cheong, W. V. Chin, B. B. Tan 2019, 'A rare cause of back pain and radiculopathy – spinal tophi: a case report', Journal of Medical Case Reportshttp://link.springer.com/article/10.1186/s13256-018-1940-4. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Histopathological findings of a nodule biopsy were consistent with gouty tophi.
Tayana Donato Alves, Isabela S. Oliveira, Luiza C. Fadul, Mittermayer B. Santiago 2014, 'Jaccoud's Arthropathy in Gout: An Unusual Association', Case Reports in Rheumatologyhttp://dx.doi.org/10.1155/2014/873189. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The tophi decreased in size peripherally with marginal improvement in back pain.
Safi Alqatari, Roberta Visevic, Nina Marshall, John Ryan, Grainne Murphy 2018, 'An unexpected cause of sacroiliitis in a patient with gout and chronic psoriasis withinflammatory arthritis: a case report', BMC Musculoskeletal Disordershttp://link.springer.com/article/10.1186/s12891-018-2044-4. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The projected time of complete resolution of all tophi was determined by linear regression analysis.
Brian F. Mandell, Anthony E. Yeo, Peter E. Lipsky 2018, 'Tophus resolution in patients with chronic refractory gout who have persistent urate-loweringresponses to pegloticase', Arthritis Research & Therapyhttp://link.springer.com/article/10.1186/s13075-018-1782-x. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Curettage of the tophi resulted in immediate improvement of knee function.
K Kobayashi, M Deie, A Okuhara, N Adachi, M Yasumoto, M Ochi 2005, 'Tophaceous Gout in the Bipartite Patella with Intra-Osseous and Intra-Articular Lesions:A Case Report', Journal of Orthopaedic Surgeryhttps://doi.org/10.1177/230949900501300219. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We report a rare localization of gouty tophi in a 52 years old male.
Ioannis K, Ippokratis P, Nazzar T 2016, 'Tophaceous Gout simulating infected Ankle Implants', Malaysian Orthopaedic Journalhttp://www.morthoj.org/2016/v10n3/tophaceous-gout.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)