thin projections extending from the edge of migrating cells
Examples of 'filopodia' in a sentence
filopodia
This process appears to be mediated by platelet filopodia that are sensitive to spatial cues.
Ashley Kita, Yumiko Sakurai, David R. Myers, Ross Rounsevell, James N. Huang, TaeJoon Seok, Kyoungsik Yu, Ming C. Wu, Daniel A. Fletcher, Wilbur A. Lam 2011, 'Microenvironmental Geometry Guides Platelet Adhesion and Spreading: A QuantitativeAnalysis at the Single Cell Level', PLoS ONE10.1371/journal.pone.0026437. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Rac1 activity in these cells was also decreased as was formation of lamellipodia and filopodia.
Maki Ohsawa, Toshiyuki Kobayashi, Hidehiro Okura, Takashi Igarashi, Masashi Mizuguchi,Okio Hino 2013, 'TSC1 Controls Distribution of Actin Fibers through Its Effect on Function of Rho Familyof Small GTPases and Regulates Cell Migration and Polarity', PLoS ONE10.1371/journal.pone.0054503. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Cells may use a similar mechanism to regulate filopodia formation along the cell leading edge.
Yaron Ideses, Yifat Brill-Karniely, Lior Haviv, Avinoam Ben-Shaul, Anne Bernheim-Groswasser 2008, 'Arp2/3 Branched Actin Network Mediates Filopodia-Like Bundles Formation In Vitro',PLoS ONE10.1371/journal.pone.0003297. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Dendritic spines on the interneurons were highly dynamic, especially the filopodia and thin spines.
Yu-Bin Huang, Chun-Rui Hu, Li Zhang, Wu Yin, Bing Hu 2015, 'In Vivo Study of Dynamics and Stability of Dendritic Spines on Olfactory Bulb Interneuronsin Xenopus laevis Tadpoles', PLOS ONE10.1371/journal.pone.0140752. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The number of filopodia extended from the cell bodies was lower for the abnormal cells.
Hung Yao-Ching, Chen Chiun-Hsun, Pan Hsu-An, Su Chia-Wei, Tai Shih-Ming, Ko Fu-Hsiang,Steve Huang G 2009, 'A Nanodot Array Modulates Cell Adhesion and Induces an Apoptosis-Like Abnormalityin NIH-3T3 Cells', Nanoscale Research Lettershttp://dx.doi.org/10.1007/s11671-009-9333-7. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Dendritic filopodia are thin, long, and highly mobile protrusions functioning as spine precursors.
Yutaka Furutani, Yoshihiro Yoshihara, Yoshihiro Yoshihara 2018, 'Proteomic Analysis of Dendritic Filopodia-Rich Fraction Isolated by Telencephalinand Vitronectin Interaction', Frontiers in Synaptic Neurosciencehttps://www.frontiersin.org/article/10.3389/fnsyn.2018.00027/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
These projections are tipped by filopodia-like structures that appear to sample the environment.
Isabelle Migeotte, Tatiana Omelchenko, Alan Hall, Kathryn V Anderson 2010, 'Rac1-dependent collective cell migration is required for specification of the anterior-posteriorbody axis of the mouse.', PLoS Biologyhttp://europepmc.org/articles/PMC2914637?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Under ultramicroscopic observation, control cells looked polymorphous with filopodia.
Y. Asara, J. A. Marchal, P. Bandiera, V. Mazzarello, L. G. Delogu, M. A. Sotgiu, A.Montella, R. Madeddu 2012, 'Cadmium influences the 5-Fluorouracil cytotoxic effects on breast cancer cells',European Journal of Histochemistryhttp://www.ejh.it/index.php/ejh/article/view/1902. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Formation of filopodia and other shape change events are vital for platelet hemostatic function.
Robert Goggs, Joshua S Savage, Harry Mellor, Alastair W Poole 2013, 'The small GTPase Rif is dispensable for platelet filopodia generation in mice.', PLoS ONEhttp://europepmc.org/articles/PMC3554654?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The mechanisms regulating filopodia formation by platelets are incompletely understood however.
Robert Goggs, Joshua S Savage, Harry Mellor, Alastair W Poole 2013, 'The small GTPase Rif is dispensable for platelet filopodia generation in mice.', PLoS ONEhttp://europepmc.org/articles/PMC3554654?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)