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单词 filovirus
释义

filovirus in British English

(ˈfaɪləʊˌvaɪrəs)
noun
any member of a family of viruses that includes the agents responsible for Ebola virus disease and Marburg disease
Word origin
C20: from Latin filum thread + virus

filovirus in American English

(ˈfɪləˌvairəs, ˈfailə-)
nounWord forms: plural -ruses
any of several viruses that are members of the new virus family Filoviridae, defined by their unique appearance and reproductive strategies, as the Ebola and Marburg viruses

Examples of 'filovirus' in a sentence
filovirus

There are no currently approved treatments for filovirus infections.
Sina Bavari, Rekha G. Panchal, Dan V. Mourich, Lisa S. Welch, Nicole L. Garza, JayB. Wells, Travis K. Warren, Patrick L. Iversen 2012, 'Discovery and Early Development of AVI-7537 and AVI-7288 for the Treatment of EbolaVirus and Marburg Virus Infections', Viruseshttp://www.mdpi.com/1999-4915/4/11/2806. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
This phenomenon parallels shedding of a secretory glycoprotein component in filovirus replication.
Branco Luis M, Garry Robert F 2009, 'Characterization of the Lassa virus GP1 ectodomain shedding: implications for improveddiagnostic platforms', Virology Journalhttp://www.virologyj.com/content/6/1/147. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
No approved vaccines or therapies exist for filovirus infections, despite an urgent need.
Kendra J. Alfson, Laura E. Avena, Gabriella Worwa, Ricardo Carrion, Anthony Griffiths 2017, 'Development of a Lethal Intranasal Exposure Model of Ebola Virus in the CynomolgusMacaque', Viruseshttps://www.mdpi.com/1999-4915/9/11/319. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Some methods involve removing paperwork and other objects from the filovirus disease ward without disinfection.
Silja Bühler, Paul Roddy, Ellen Nolte, Matthias Borchert 2014, 'Clinical Documentation and Data Transfer from Ebola and Marburg Virus Disease Wardsin Outbreak Settings: Health Care Workers' Experiences and Preferences', Viruseshttp://www.mdpi.com/1999-4915/6/2/927. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Filovirus antivirals are currently not clinically available.
Bethany A Rhein, Linda S Powers, Kai Rogers, Manu Anantpadma, Brajesh K Singh, YasuteruSakurai, Thomas Bair, Catherine Miller-Hunt, Patrick Sinn, Robert A Davey, MarthaM Monick, Wendy Maury 2015, 'Interferon-γ Inhibits Ebola Virus Infection.', PLoS Pathogenshttp://europepmc.org/articles/PMC4643030?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The mortality rate in filovirus infections can be up to 90%.
Orhan BAYLAN, Levent DOĞANCI, Hüseyin GÜN 1997, 'Filoviridae Infections', Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisihttp://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=1997-2-3-164-169.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
However, in comparison, the seven other known filovirus family members are significantly understudied.
Scott M. Anthony, Steven B. Bradfute 2015, 'Filoviruses: One of These Things is (not) Like the Other', Viruseshttp://www.mdpi.com/1999-4915/7/10/2867. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Specifically, identifying potential reservoir species with the expected long-term coevolutionary history of filovirus infections has been intractable.
Bruenn Jeremy, Leach Robert W, Taylor Derek J 2010, 'Filoviruses are ancient and integrated into mammalian genomes', BMC Evolutionary Biologyhttp://www.biomedcentral.com/1471-2148/10/193. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Here, we describe two methods for production and purification of filovirus glycoproteins in insectand mammalian cell lines.
Elizabeth C. Clarke, Amanda L. Collar, Chunyan Ye, Yíngyún Caì, Eduardo Anaya, DerekRinaldi, Britney Martinez, Sarah Yarborough, Christine Merle, Manfred Theisen, JiroWada, Jens H. Kuhn, Steven B. Bradfute 2017, 'Production and Purification of Filovirus Glycoproteins in Insect and Mammalian CellLines', Scientific Reportshttp://link.springer.com/article/10.1038/s41598-017-15416-3. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
During the last ten years, important progress has been made in understanding the molecular mechanisms of filovirus pathogenesis.
Washington B. Cárdenas 2010, 'Evasion of the Interferon-Mediated Antiviral Response by Filoviruses', Viruseshttp://www.mdpi.com/1999-4915/2/1/262/. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
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更新时间：2024/12/22 17:25:16