pathology with emphasis on the biological aspects of disease
Examples of 'pathobiology' in a sentence
pathobiology
We have assessed the pathogenicity, pathobiology and immunological responses associated with thisvirus in chickens.
Jeffrey Butler, Cameron R Stewart, Daniel S Layton, Phouvong Phommachanh, JenniferHarper, Jean Payne, Ryan M Evans, Stacey Valdeter, Som Walker, Gemma Harvey, SonghuaShan, Matthew P Bruce, Christina L Rootes, Tamara J Gough, Andreas Rohringer, GrantleyR Peck, Sarah J Fardy, Adam J Karpala, Dayna Johnson, Jianning Wang, Bounlom Douangngeun,Christopher Morrissy, Frank Y K Wong, Andrew G D Bean, John Bingham, David T Williams 2016, 'Novel Reassortant H5N6 Influenza A Virus from the Lao People's Democratic RepublicIs Highly Pathogenic in Chickens.', PLoS ONEhttp://europepmc.org/articles/PMC5025169?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Hence, further investigations are essential for understanding the right ventricular pathobiology.
Doreen eKöhler, Raoul eArnold, Tsvetomir eLoukanov, Matthias eGorenflo 2013, 'Right ventricular failure and pathobiology in patients with congenital heart disease– implications for long-term follow-up', Frontiers in Pediatricshttp://journal.frontiersin.org/Journal/10.3389/fped.2013.00037/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Inflammation has been reported to constitute a major component of ischemic stroke pathobiology.
Ayman eElAli, Ayman eElAli, Noëmie eJean-Leblanc 2016, 'The role of monocytes in ischemic stroke pathobiology: New avenues to explore', Frontiers in Aging Neurosciencehttp://journal.frontiersin.org/Journal/10.3389/fnagi.2016.00029/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Despite extensive research, progress has been slow in understanding the pathobiology.
Madhuri Thumuluru Kavitha, Tailor Anil, Haagsma Ben, Coley Helen, Butler-Manuel Simon 2012, 'Relevance of immunohistochemical expression of p57kip2 in epithelial ovariancarcinoma- A systematic literature review', Journal of Ovarian Researchhttp://www.ovarianresearch.com/content/5/1/46. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Blood has been useful in studying the pathobiology of many diseases.
Heesun Shin, Casey P Shannon, Nick Fishbane, Jian Ruan, Mi Zhou, Robert Balshaw, JanetE Wilson-McManus, Raymond T Ng, Bruce M McManus, Scott J Tebbutt 2014, 'Variation in RNA-Seq transcriptome profiles of peripheral whole blood from healthyindividuals with and without globin depletion.', PLoS ONEhttp://europepmc.org/articles/PMC3946641?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
These alterations may play roles in the pathobiology of this disease.
Ikeda H, Ishiguro K, Igarashi T, Aoki Y, Hayashi T, Ishida T, Sasaki Y, Tokino T,Shinomura Y 2015, 'Molecular diagnostics of a single drug-resistant multiple myeloma case using targetednext-generation sequencing', OncoTargets and Therapyhttps://www.dovepress.com/molecular-diagnostics-of-a-single-drug-resistant-multiple-myeloma-case-peer-reviewed-article-OTT. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Thus, they are important candidates for biomarker studies and understanding cancer pathobiology.
Shahid Hussain, Sonal Saxena, Sameer Shrivastava, Ashok Kumar Mohanty, Sudarshan Kumar,Rajkumar James Singh, Abhinav Kumar, Sajad Ahmad Wani, Ravi Kumar Gandham, NaveenKumar, Anil Kumar Sharma, Ashok Kumar Tiwari, Raj Kumar Singh 2018, 'Gene expression profiling of spontaneously occurring canine mammary tumours: Insightinto gene networks and pathways linked to cancer pathogenesis.', PLoS ONEhttp://europepmc.org/articles/PMC6281268?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
These markers may be indicators of pathobiology but will need to be further investigated.
Felix Leung, Marcus Q. Bernardini, Kun Liang, Ihor Batruch, Marjan Rouzbahman, EleftheriosP. Diamandis, Vathany Kulasingam 2018, 'Unraveling endometriosis-associated ovarian carcinomas using integrative proteomics[version 2; referees: 2 approved]', F1000Researchhttps://f1000research.com/articles/7-189/v2. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We expect to foster debate on the underlining basis of age-related cancer pathobiology.
Abdelouahid eElkhattouti, Mohamed eHassan, Christian eGomez 2015, 'Stromal Fibroblast in Age-related Cancer: Role in Tumorigenesis and Potential as NovelTherapeutic Target', Frontiers in Oncologyhttp://journal.frontiersin.org/Journal/10.3389/fonc.2015.00158/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The immune system plays a fundamental role in both the development and pathobiology of stroke.
Jing Zhao, Yongshan Mou, Joshua D Bernstock, Dace Klimanis, Sixian Wang, Maria Spatz,Dragan Maric, Kory Johnson, Dennis M Klinman, Xiaohong Li, Xinhui Li, John M Hallenbeck 2015, 'Synthetic Oligodeoxynucleotides Containing Multiple Telemeric TTAGGG Motifs SuppressInflammasome Activity in Macrophages Subjected to Oxygen and Glucose Deprivation andReduce Ischemic Brain Injury in Stroke-Prone Spontaneously Hypertensive Rats.', PLoS ONEhttp://europepmc.org/articles/PMC4608557?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)