one of a layer of enamel-secreting cells covering the dentin of a developing tooth
Derived forms
ameloblastic
adjective
Word origin
[1875–80; (en)amel + -o- + -blast]This word is first recorded in the period 1875–80. Other words that entered Englishat around the same time include: authoritarian, cross-fertilization, hat trick, knockabout, neoclassic-o- is the typical ending of the first element of compounds of Greek origin (as -i- is, in compounds of Latin origin), used regularly in forming new compounds with elementsof Greek origin and often used in English as a connective irrespective of etymology(Franco-Italian; geography; seriocomic; speedometer); -blast is a suffix meaning “bud, sprout,” “embryo,” “formative cells or cell layer”. Otherwords that use the affix -blast include: hypoblast, myoblast, odontoblast, spongioblast, trophoblast
Examples of 'ameloblast' in a sentence
ameloblast
The ameloblast membrane resides at the interface between matrix and cell.
Cong-Dat Pham, Charles E. Smith, Charles E. Smith, Yuanyuan Hu, Jan C-C. Hu, JamesP. Simmer, Yong-Hee P. Chun, Yong-Hee P. Chun 2017, 'Endocytosis and Enamel Formation', Frontiers in Physiologyhttp://journal.frontiersin.org/article/10.3389/fphys.2017.00529/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Histological examination of tissue sections, showed differences in ameloblast and odontoblastic layers.
Medhat Ahmed El-Zainy, Khaled Nour El-Haddad, Raneem Farouk Obeid 2017, 'Efficacy of transforming growth factor- β on development of ameloblasts and odontoblastsin tooth germ of young albino rat', Future Dental Journalhttp://www.sciencedirect.com/science/article/pii/S2314718017300319. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Gingival epithelial cells differentiated into ameloblast-like cells through epithelial-mesenchymal transition.
Sun-Yi Hyun, Seyoung Mun, Kyung-Jung Kang, Jong-Chan Lim, Shin-Young Kim, KyudongHan, Young-Joo Jang 2019, 'Amelogenic transcriptome profiling in ameloblast-like cells derived from adult gingivalepithelial cells', Scientific Reportshttp://link.springer.com/article/10.1038/s41598-019-40091-x. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Furthermore, a cyst-like structure was observed during late ameloblast maturation.
Kan Saito, Emiko Fukumoto, Aya Yamada, Kenji Yuasa, Keigo Yoshizaki, Tsutomu Iwamoto,Masahiro Saito, Takashi Nakamura, Satoshi Fukumoto 2015, 'Interaction between fibronectin and β1 integrin is essential for tooth development.',PLoS ONEhttp://europepmc.org/articles/PMC4382024?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The odontogenic epithelium exhibited peripheral ameloblast-like and central stellate reticulum-like cells.
Shiny Joseph, Lakshmi Priya, Dinesh Gopal, Mary Devachen, Ajay Narayan, Muhammed Afnan 2015, 'Ameloblastic Fibrodentinoma Presenting as a False Gingival Enlargement in the MaxillaryAnterior Region', Case Reports in Dentistryhttp://dx.doi.org/10.1155/2015/812087. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The molecular mechanisms of ameloblast differentiation (amelogenesis) are currently not well understood.
Trianna W. Utami, Keiko Miyoshi, Hiroko Hagita, Ryna Dwi Yanuaryska, Taigo Horiguchi,Takafumi Noma 2011, 'Possible Linkage of SP6 Transcriptional Activity with Amelogenesis by Protein Stabilization',Journal of Biomedicine and Biotechnologyhttp://dx.doi.org/10.1155/2011/320987. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
These cell surface markers might be useful for the detection and isolation of ameloblast-like cells from dental tissues.
Sun-Yi Hyun, Seyoung Mun, Kyung-Jung Kang, Jong-Chan Lim, Shin-Young Kim, KyudongHan, Young-Joo Jang 2019, 'Amelogenic transcriptome profiling in ameloblast-like cells derived from adult gingivalepithelial cells', Scientific Reportshttp://link.springer.com/article/10.1038/s41598-019-40091-x. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Owing to these, little was known about appropriate cell surface markers to isolate ameloblast-like cells in tissues.
Sun-Yi Hyun, Seyoung Mun, Kyung-Jung Kang, Jong-Chan Lim, Shin-Young Kim, KyudongHan, Young-Joo Jang 2019, 'Amelogenic transcriptome profiling in ameloblast-like cells derived from adult gingivalepithelial cells', Scientific Reportshttp://link.springer.com/article/10.1038/s41598-019-40091-x. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
At the further step of differentiation, epithelial ameloblast and mesenchymal odontoblast will deposit organic matrix in enamel and dentin.
Yani Corvianindya, Elza Ibrahim Auerkari 2015, 'Morfogenesis dan Diferensiasi Sel dalam Perkembangan Gigi (Tinjauan Molekuler)', Journal of Dentistry Indonesiahttp://jdentistry.ui.ac.id/index.php/JDI/article/view/943. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Several reports have indicated that biglycan participates in odontoblast and ameloblast differentiation and in the calcification process.
D.M.H. Tenório, M.F. Santos, T.M.T. Zorn 2003, 'Distribution of biglycan and decorin in rat dental tissue', Brazilian Journal of Medical and Biological Researchhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000800012. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)