of or pertaining to peptides; of the nature of peptides
Examples of 'peptidic' in a sentence
peptidic
Both types of macrocycles are steroid-peptoid hybrid macrocycles containing exocyclic peptidic chains.
Ludger A. Wessjohann, Daniel G. Rivera 2007, 'Synthesis of Novel Steroid-Peptoid Hybrid Macrocycles by Multiple Multicomponent MacrocyclizationsIncluding Bifunctional Building Blocks (MiBs)', Moleculeshttp://www.mdpi.com/1420-3049/12/8/1890/. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The proteolytic stabilities of the conjugates depend on the functional peptidic epitopes.
Dan Yuan, Xuewen Du, Junfeng Shi, Ning Zhou, Abdulgader Ahmed Baoum, Khalid Omar AlFooty, Khadija Omar Badahdah, Bing Xu 2015, 'Synthesis and evaluation of the biostability and cell compatibility of novel conjugatesof nucleobase, peptidic epitope, and saccharide', Beilstein Journal of Organic Chemistryhttps://doi.org/10.3762/bjoc.11.145. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Spider venoms are rich sources of peptidic ion channel modulators with important therapeuticalpotential.
Silmara R Sousa, Joshua S Wingerd, Andreas Brust, Christopher Bladen, Lotten Ragnarsson,Volker Herzig, Jennifer R Deuis, Sebastien Dutertre, Irina Vetter, Gerald W Zamponi,Glenn F King, Paul F Alewood, Richard J Lewis 2017, 'Discovery and mode of action of a novel analgesic β-toxin from the African spiderCeratogyrus darlingi.', PLoS ONEhttp://europepmc.org/articles/PMC5589098?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Finally, these peptidic gelators could be used to quantitatively remove toxic dyes from aqueous solutions.
Jürgen Bachl, Stefan Oehm, Judith Mayr, Carlos Cativiela, José Juan Marrero-Tellado,David Díaz Díaz 2015, 'Supramolecular Phase-Selective Gelation by Peptides Bearing Side-Chain Azobenzenes:Effect of Ultrasound and Potential for Dye Removal and Oil Spill Remediation', International Journal of Molecular Scienceshttp://www.mdpi.com/1422-0067/16/5/11766. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Therefore, the search for new efficient non-peptidic inhibitors has been undertaken by many scientific groups.
Marek Bajda, Jakub Jończyk, Barbara Malawska, Sławomir Filipek 2014, 'Application of Computational Methods for the Design of BACE-1 Inhibitors: Validationof in Silico Modelling', International Journal of Molecular Scienceshttp://www.mdpi.com/1422-0067/15/3/5128. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
However, more recently a potent non-peptidic inhibitor of renin, aliskiren, with acceptable oral bioavailability, has been synthesised.
Alice Stanton 2003, 'Review: Potential of renin inhibition in cardiovascular disease', Journal of the Renin-Angiotensin-Aldosterone Systemhttps://doi.org/10.3317/jraas.2003.008. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Recently, an innovative mass-spectrometry-based strategy, peptidogenomics, has been pioneered to effectively mine microbial strains for novel peptidic metabolites.
Marnix H Medema, Yared Paalvast, Don D Nguyen, Alexey Melnik, Pieter C Dorrestein,Eriko Takano, Rainer Breitling 2014, 'Pep2Path: automated mass spectrometry-guided genome mining of peptidic natural products.',PLoS Computational Biologyhttp://europepmc.org/articles/PMC4154637?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Coumarins (chromen-2-ones) are considered a privileged structure for designing novel orally bioavailable and non-peptidic antiviral agents.
Ilaria Conti, Rita Morigi, Alessandra Locatelli, Mirella Rambaldi, Gloria Bua, GiorgioGallinella, Alberto Leoni 2019, 'Synthesis of 3-(Imidazo[2,1-b]thiazol-6-yl)-2H-chromen-2-one Derivatives and Studyof Their Antiviral Activity against Parvovirus B19', Moleculeshttp://www.mdpi.com/1420-3049/24/6/1037. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Our results highlight a potential, previously undescribed molecular mechanism by which peptidic vinca-site agents maintain unparalleled potency as microtubule-destabilizing agents.
Andrew B. Waight, Katja Bargsten, Svetlana Doronina, Michel O. Steinmetz, Django Sussman,Andrea E. Prota 2016, 'Structural Basis of Microtubule Destabilization by Potent Auristatin Anti-Mitotics',PLOS ONE10.1371/journal.pone.0160890. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Peptidic fractions with higher radical scavenging activity were analysed by matrix-assisted laser desorption/ionization mass spectrometry.
Santiago Gallegos Tintoré, Cristina Torres Fuentes, Javier Solorza Feria, Manuel Alaiz,Julio Girón Calle, Alma Leticia Martínez Ayala, Luis Chel Guerrero, Javier Vioque 2015, 'Antioxidant and Chelating Activity of Nontoxic Jatropha curcas L. Protein HydrolysatesProduced by In Vitro Digestion Using Pepsin and Pancreatin', Journal of Chemistryhttp://dx.doi.org/10.1155/2015/190129. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)