Lesions were unilateral, ie, three macular, two juxtapapillary and macular, and one pericentral.
Bruè C, Saitta A, Nicolai M, Mariotti C, Giovannini A 2013, 'Epiretinal membrane surgery for combined hamartoma of the retina and retinal pigmentepithelium: role of multimodal analysis', Clinical Ophthalmologyhttp://www.dovepress.com/epiretinal-membrane-surgery-for-combined-hamartoma-of-the-retina-and-r-a12018. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
This allows for inclusion of zonated enzyme expression by splitting the sinusoid into periportal to pericentral compartments.
William B Ashworth, Nathan A Davies, I David L Bogle 2016, 'A Computational Model of Hepatic Energy Metabolism: Understanding Zonated Damage andSteatosis in NAFLD.', PLoS Computational Biologyhttp://europepmc.org/articles/PMC5025084?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
He had a 4.0 × 3.0 mm area of pericentral corneal ulcer with deep corneal stromal infiltration and 2 mm hypopyon.
A. Altun, S. A. Kurna, T. Sengor, G. Altun, O. O. Olcaysu, S. F. Aki, M. H. Simsek 2014, 'Effectiveness of Posaconazole in Recalcitrant Fungal Keratitis Resistant to ConventionalAntifungal Drugs', Case Reports in Ophthalmological Medicinehttp://dx.doi.org/10.1155/2014/701653. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Several differences between zones contributed to a higher susceptibility to steatosis in pericentral cells in the model simulations.
William B Ashworth, Nathan A Davies, I David L Bogle 2016, 'A Computational Model of Hepatic Energy Metabolism: Understanding Zonated Damage andSteatosis in NAFLD.', PLoS Computational Biologyhttp://europepmc.org/articles/PMC5025084?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)