an oestrogen that occurs naturally in soya beans and is believed to inhibit the growth of certain tumours
Examples of 'genistein' in a sentence
genistein
This study was designed to evaluate the effect of ovariectomy on nutrikinetics of genistein metabolites.
Da-Hye Lee, Min Jung Kim, Eun-Ji Song, Jin Hee Kim, Jiyun Ahn, Young-Do Nam, Young-JinJang, Tae-Youl Ha, Chang Hwa Jung 2017, 'Nutrikinetic study of genistein metabolites in ovariectomized mice', PLOS ONE10.1371/journal.pone.0186320. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The amount of genistein may be a major regulatory factor in soybean-rhizobium compatibility.
Clarissien Ramongolalaina, Masayoshi Teraishi, Yutaka Okumoto 2018, 'QTLs underlying the genetic interrelationship between efficient compatibility of Bradyrhizobiumstrains with soybean and genistein secretion by soybean roots.', PLoS ONEhttp://europepmc.org/articles/PMC5884529?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In conclusion, genistein treatment decreases cell growth and proliferation in colon cancer cell lines.
Huan Wang, Qian Li, Hong Chen 2012, 'Genistein affects histone modifications on Dickkopf-related protein 1 (DKK1) genein SW480 human colon cancer cell line.', PLoS ONEhttp://europepmc.org/articles/PMC3399800?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Effects of genistein on insulin release have also been showed.
Elizabeth Adriana ESTEVES, Josefina Bressan Resende MONTEIRO 2001, 'Efeitos benéficos das isoflavonas de soja em doencas crônicas Beneficial effects ofsoy isoflavones on chronic diseases', Revista de Nutriçãohttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-52732001000100007. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In addition, genistein has been suggested to have antiangiogenic and antioxidant activities.
Jung-Yun Lee, Hee Seung Kim, Yong-Sang Song, MD, PhD 2012, 'Genistein as a Potential Anticancer Agent against Ovarian Cancer', Journal of Traditional and Complementary Medicinehttp://www.sciencedirect.com/science/article/pii/S2225411016300827. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
But the sterol regulatory element deletion mutant construct failed to be activated by genistein.
Medicia Kartawijaya, Hye Won Han, Yunhye Kim, Seung-Min Lee 2016, 'Genistein upregulates LDLR levels via JNK-mediated activation of SREBP-2', Food & Nutrition Researchhttp://www.foodandnutritionresearch.net/index.php/fnr/article/view/31120/46756. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The cellular antioxidant capacity and inhibitory effect of genistein were confirmed.
Sang-Hyun Lee, Jin-Kyoung Kim, Hae-Dong Jang 2014, 'Genistein Inhibits Osteoclastic Differentiation of RAW 264.7 Cells via Regulationof ROS Production and Scavenging', International Journal of Molecular Scienceshttp://www.mdpi.com/1422-0067/15/6/10605. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Genistein-treated cells were less invasive and less motile than untreated cells.
Nakamura Atsushi, Aizawa Junichi, Sakayama Kenshi, Kidani Teruki, Takata Tomoyo, NorimatsuYoshiaki, Miura Hiromasa, Masuno Hiroshi 2012, 'Genistein inhibits cell invasion and motility by inducing cell differentiation inmurine osteosarcoma cell line LM8', BMC Cell Biologyhttp://www.biomedcentral.com/1471-2121/13/24. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The level of β-catenin was higher in genistein-treated cells than in untreated cells.
Nakamura Atsushi, Aizawa Junichi, Sakayama Kenshi, Kidani Teruki, Takata Tomoyo, NorimatsuYoshiaki, Miura Hiromasa, Masuno Hiroshi 2012, 'Genistein inhibits cell invasion and motility by inducing cell differentiation inmurine osteosarcoma cell line LM8', BMC Cell Biologyhttp://www.biomedcentral.com/1471-2121/13/24. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The effects caused by genistein were similar to those of adiponectin.
Elena Grossini, Serena Farruggio, Giulia Raina, David Mary, Giacomo Deiro, SergioGentilli 2018, 'Effects of Genistein on Differentiation and Viability of Human Visceral Adipocytes',Nutrientshttp://www.mdpi.com/2072-6643/10/8/978. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)