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单词 peroxisomal
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peroxisomal

Organic acidurias have been the most frequently detected diseases, followed by aminoacidopathies and peroxisomal disorders.In this study, mitochondrial and peroxisomal reactions are considered critical in ischemic tolerance.Peroxisomal disorders are a group of genetically heterogeneous metabolic diseases related to dysfunction of peroxisomes.Recent studies have highlighted the association between peroxisomal dysfunction and hepatic steatosis.This case suggests that next-generation sequencing may be diagnostic in some atypical peroxisomal biogenesis disorders.Here, we focus on mechanisms leading to dual targeting of peroxisomal proteins.Peroxisomal matrix proteins are synthesized cytosolically and posttranslationally imported into the peroxisomal matrix.The size of the peroxisomal compartment did not correlate with neuronal death.Different peroxisomal functions contribute to the orchestration of this complex developmental process.Here the authors engineer a peroxisomal protein import pathway orthogonal to the naturally occurring system.
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