a colourless insoluble aromatic liquid obtained from coal tar and used in the manufacture of synthetic resins. Formula: C8H6O
Also called: coumarone, cumarone
Examples of 'benzofuran' in a sentence
benzofuran
They contain benzofuran and indole radicals correspondingly in position 2 of triazole ring.
A. K. Bilyi, S. I. Kovalenko, O. V. Prihodko 2013, 'Investigation of growth stimulating activity of 2-heteryl-[1,2,4]triazolo [1,5-c]quinazolinesand products of its nucleophilic degradation', Zaporožskij Medicinskij Žurnalhttp://zmj.zsmu.edu.ua/article/view/15606/13406. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Chemical synthesis of benzofuran rings often requires expensive catalysts and stringent operational conditions.
Xin Liu, Weiwei Wang, Haiyang Hu, Xinyu Lu, Lige Zhang, Ping Xu, Hongzhi Tang 2018, '2-Hydroxy-4-(3′-oxo-3′H-benzofuran-2′-yliden)but-2-enoic acid biosynthesis from dibenzofuranusing lateral dioxygenation in a Pseudomonas putida strain B6-2 (DSM 28064)', Bioresources and Bioprocessinghttp://link.springer.com/article/10.1186/s40643-018-0209-5. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Ring-closure reactions to afford quinoline, benzofuran, indene, and heterocyclic common rings are also catalyzed.
Sayoko Nagashima, Satoshi Kamiguchi, Teiji Chihara 2014, 'Catalytic Reactions over Halide Cluster Complexes of Group 5–7 Metals', Metalshttp://www.mdpi.com/2075-4701/4/2/235. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
A certain influence of the benzofuran substituents concerning absorption and fluorescent properties was observed.
Costel Moldoveanu, Ionel Mangalagiu, Dragos Lucian Isac, Anton Airinei, GheorghitaZbancioc 2018, 'A New Pathway for the Synthesis of a New Class of Blue Fluorescent Benzofuran Derivatives',Moleculeshttp://www.mdpi.com/1420-3049/23/8/1968. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Among the tested compounds the terminal aromatic ring benzofuran showed the best activity.
Jane Thanassi, Michael J. Pucci, Tarek Aboul-Fadl, Hatem A. Abdel-Aziz, Tilal Elsaman,Mohammed K. Abdel-Hamid 2011, 'Schiff Bases of Indoline-2,3-dione: Potential Novel Inhibitors of Mycobacterium Tuberculosis(Mtb) DNA Gyrase', Moleculeshttp://www.mdpi.com/1420-3049/16/9/7864/. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The indole derivatives formed in aprotic solvents, the benzofuran derivatives were obtained in acidic medium.
S. A. Konovalova, A. P. Avdeenko, E. N. Lysenko, A. L. Yusina 2017, 'SYNTHESIS OF BENZOFURAN DERIVATIVES ON THE BASIS OF N-ACYL-1,4-BENZOQUINONE MONOIMINES',Vìsnik Odesʹkogo Nacìonalʹnogo Unìversitetu: Hìmìâhttp://heraldchem.onu.edu.ua/article/view/102211. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
A new series of 2-alkyloxy-pyridine-3-carbonitrile-benzofuran hybrids (4a–x) was synthesized.
Nagy M. Khalifa, Aladdin M. Srour, Somaia S. Abd El-Karim, Dalia O. Saleh, MohamedA. Al-Omar 2017, 'Synthesis and 2D-QSAR Study of Active Benzofuran-Based Vasodilators', Moleculeshttps://www.mdpi.com/1420-3049/22/11/1820. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Here, feasible reaction mechanisms for the benzofuran derivatives formation are described.
Costel Moldoveanu, Ionel Mangalagiu, Dragos Lucian Isac, Anton Airinei, GheorghitaZbancioc 2018, 'A New Pathway for the Synthesis of a New Class of Blue Fluorescent Benzofuran Derivatives',Moleculeshttp://www.mdpi.com/1420-3049/23/8/1968. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)