[1930–35; spasm + -o- + -lytic]This word is first recorded in the period 1930–35. Other words that entered Englishat around the same time include: DNA, boondoggle, cloverleaf, kickback, old school tie-o- is the typical ending of the first element of compounds of Greek origin (as -i- is, in compounds of Latin origin), used regularly in forming new compounds with elementsof Greek origin and often used in English as a connective irrespective of etymology(Franco-Italian; geography; seriocomic; speedometer); -lytic is a combining form occurring in adjectives that correspond to nouns ending in -lysis. Other words that use the affix -lytic include: analytic, paralytic
Examples of 'spasmolytic' in a sentence
spasmolytic
These results suggest the use of curcuma extract as a spasmolytic agent.
Rita Aldini, Roberta Budriesi, Giulia Roda, Matteo Micucci, Pierfranco Ioan, AntoniaD'Errico-Grigioni, Alessandro Sartini, Elena Guidetti, Margherita Marocchi, MonicaCevenini, Francesca Rosini, Marco Montagnani, Alberto Chiarini, Giuseppe Mazzella 2012, 'Curcuma longa extract exerts a myorelaxant effect on the ileum and colon in a mouseexperimental colitis model, independent of the anti-inflammatory effect.', PLoS ONEhttp://europepmc.org/articles/PMC3440350?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The spasmolytic action of the extract was also assessed on contraction induced by acetylcholine and high potassium.
Acharaporn Duangjai, Bey-Hing Goh, Learn-Han Lee, Surasak Saokaew 2018, 'Relaxant effects of Azadirachta indica A. Juss var. siamensis Valeton flower extracton isolated rat ileum contractions and the mechanisms of action', Journal of Traditional and Complementary Medicinehttp://www.sciencedirect.com/science/article/pii/S2225411018300038. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Parietal cell atrophy in a setting of chronic inflammation induces spasmolytic polypeptide expressing metaplasia, a critical step in gastric carcinogenesis.
Kevin A. Bockerstett, Luciana H. Osaki, Christine P. Petersen, Catherine W. Cai, ChunFung Wong, Thanh-Long M. Nguyen, Eric L. Ford, Daniel F. Hoft, Jason C. Mills, JamesR. Goldenring, Richard J. DiPaolo 2018, 'Interleukin-17A Promotes Parietal Cell Atrophy by Inducing ApoptosisSummary', Cellular and Molecular Gastroenterology and Hepatologyhttp://www.sciencedirect.com/science/article/pii/S2352345X17301911. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The solvent-solvents fractionation reflected segregations of spasmogenic and spasmolytic effects in respective aqueous and dichloromethane fractions.
Khalid Hussain Janbaz, Fatima Saqib 2015, 'Pharmacological evaluation of Dactyloctenium aegyptium: An indigenous plant used tomanage gastrointestinal ailments', Bangladesh Journal of Pharmacologyhttp://www.banglajol.info/index.php/BJP/article/view/21811. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Documented evidence showed that the leaves of the plant possess spasmolytic, analgesic, anti-inflammatory and antipyretic activities.
Elham Amin, Mohamed M. Radwan, Seham S. El-Hawary, Magda M. Fathy, Rabab Mohammed,James J. Becnel, Ikhlas Khan 2012, 'Potent Insecticidal Secondary Metabolites from the Medicinal Plant Acanthus montanus',Records of Natural Productshttp://www.acgpubs.org/RNP/2012/Volume%206/Issue%201/42-RNP-1103-564.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Flavonoids and other phenolic constituents with a spasmolytic effect were detected in only 20% of the samples from each group.
Maria G. Lins Brandão, Noélia Freire, Cristina D. Vianna-Soares 1998, 'Vigilância de fitoterápicos em Minas Gerais. Verificação da qualidade de diferentesamostras comerciais de camomila Surveillance of phytotherapeutic drugs in the Stateof Minas Gerais. Quality assessment of commercial samples of chamomile', Cadernos de Saúde Públicahttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X1998000300018. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The spasmolytic action of the same extract concentrations was also examined on contraction induced by 10-4 acetylcholine.
Seyed Hassan Hejazian, Seyyed Majid Bagheri, Mohammad Hossein Dashti-R 2014, 'Relaxant effect of Humulus lupulus extracts on isotonic rat's ileum contractions',Avicenna Journal of Phytomedicinehttp://ajp.mums.ac.ir/pdf_1171_72ed29309122bc9346c1b8378a5680d1.html. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Results of in vitro study indicated that hydroalcoholic extract of ginger contained spasmogenic and spasmolytic constituents.
Amin Mamaghani, Masoud Maham, Bahram Dalir-Naghadeh 2013, 'Effects of ginger extract on smooth muscle activity of sheep reticulum and rumen',Veterinary Research Forumhttp://www.urmia.ac.ir/vrf/Shared%20Documents/pdf/vol-4%20no-2/91-97-0364.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)