(in nucleic acid) the substitution of a purine for a pyrimidine, or vice versa, by mutation
Examples of 'transversion' in a sentence
transversion
We identified six polymorphic sites, including five insertion/deletion (indels) types and one transversion.
Nidia Gutiérrez-López, Isidro Ovando-Medina, Miguel Salvador-Figueroa, Francisco Molina-Freaner,Carlos H. Avendaño-Arrazate, Alfredo Vázquez-Ovando 2016, 'Unique haplotypes of cacao trees as revealed by trnH-psbA chloroplast DNA', PeerJhttps://peerj.com/articles/1855.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Each type of transition occurred approximately four times more frequently than each type of transversion.
Zhao Zhongming, Jiang Cizhong 2006, 'Directionality of point mutation and 5-methylcytosine deamination rates in the chimpanzeegenome', BMC Genomicshttp://www.biomedcentral.com/1471-2164/7/316. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The variations were caused by the transition substitution mutation (35.39%) and transversion substitutionmutation (64.61%).
Dewi Indriyani Roslim, Fitriyatun Nisa, Herman Herman 2016, 'An Analysis of Partial DNA Sequence of Meisa1 Gene on Sweet and Bitter Cassavas (Manihotesculenta Crantz.)', Biosaintifika: Journal of Biology & Biology Educationhttps://journal.unnes.ac.id/nju/index.php/biosaintifika/article/view/5365. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Nucleotide substitution primarily occurred through transition rather than transversion.
Nan Zarchi Win, Eun Young Choi, Deok-Jin Jang, Jinyoung Park, Jong Kyun Park 2015, 'Molecular comparison of the genus Junonia (Lepidoptera: Nymphalidae) in Myanmar',Journal of Asia-Pacific Biodiversityhttp://www.sciencedirect.com/science/article/pii/S2287884X15000771. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The estimated transitions/transversion ratio was 0.7.
Nahla M. Wassim 2012, 'Isolation of acetylcholinesterase gene from Egyptian Anopheles pharoensis (Theobald)',Journal of Basic and Applied Zoologyhttp://www.sciencedirect.com/science/article/pii/S209098961200032X. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
This indicates that a transversion mutation had a higher probability than transition and insertion mutations.
Nilly Sulistyorini, Ahmad Yudianto, Nola Margaret 2017, 'NUCLEOTIDE VARIANCE OF MITOCHONDRIAL DNA D-Loop 126 bp (nt: 34-159) REGION IN MADURESE',Folia Medica Indonesianahttps://e-journal.unair.ac.id/FMI/article/view/5215. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Furthermore, transition errors were 48-times more common than transversion errors (0.052% vs. 0.001%; p<0.0001).
Johanna Brodin, Mattias Mild, Charlotte Hedskog, Ellen Sherwood, Thomas Leitner, BjörnAndersson, Jan Albert 2013, 'PCR-induced transitions are the major source of error in cleaned ultra-deep pyrosequencingdata.', PLoS ONEhttp://europepmc.org/articles/PMC3720931?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Guanine, however, can be oxidized as an epigenetic change which can undergo base-pair transversion, causing a genetic difference.
Joonghoon Park, Jong Woo Park, Hawmok Oh, Fernanda S. Maria, Jaeku Kang, Xiuchun Tian 2016, 'Gene-Specific Assessment of Guanine Oxidation as an Epigenetic Modulator for CardiacSpecification of Mouse Embryonic Stem Cells', PLOS ONE10.1371/journal.pone.0155792. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)