the delicate web of connective tissue that surrounds and supports nerve cells
Also called: neuroglia
Derived forms
glial (ˈglial)
adjective
glia in American English
(ˈglaɪə; also ˈgliə)
noun
neuroglia
Derived forms
glial (ˈglial)
adjective
glia in American English
(ˈɡlaiə, ˈɡliə)
noun
Anatomy
neuroglia
Derived forms
glial
adjective
Word origin
[1885–90; ‹ LGk glía glue]This word is first recorded in the period 1885–90. Other words that entered Englishat around the same time include: booster, foregut, reactor, scrum, upsweep
Examples of 'glia' in a sentence
glia
Viral tropism for astrocytes was initially verified in vitro in primary mixed glia cultures.
Michael Fassler, Itai Weissberg, Nitzan Levy, Felipe Diaz-Griffero, Alon Monsonego,Alon Friedman, Ran Taube 2013, 'Preferential Lentiviral Targeting of Astrocytes in the Central Nervous System', PLoS ONE10.1371/journal.pone.0076092. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Glia activation in the spinal cord has become an attractive target for attenuating chronic pain.
Ouyang Handong, Zheng Wenwen, Zheng Xuexing, Liu Shue, Mata Marina, Fink David J,Hao Shuanglin 2011, 'Glial TNFα in the spinal cord regulates neuropathic pain induced by HIV gp120 applicationin rats', Molecular Painhttp://www.molecularpain.com/content/7/1/40. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Most studies suggest newborn cells remain undifferentiated or differentiate into glia within the adult midbrain.
Anupama Dey, Parisa Farzanehfar, Elena V. Gazina, Tim D. Aumann 2017, 'Electrophysiological and gene expression characterization of the ontogeny of nestin-expressingcells in the adult mouse midbrain', Stem Cell Researchhttp://www.sciencedirect.com/science/article/pii/S1873506117301253. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
These radial glia fibers thickened toward the pial surface, where they formed glial end feet.
A Alunni, S Vaccari, S Torcia 2009, 'Characterization of glial fibrillary acidic protein and astroglial architecture inthe brain of a continuously growing fish, the rainbow trout', European Journal of Histochemistryhttps://www.ejh.it/index.php/ejh/article/view/940. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
This includes neurons, glia and their progenitors in the brain.
Nachen Yang, Mikiko Inaki, Adam Cliffe, Pernille Rørth 2012, 'Microtubules and Lis-1/NudE/dynein regulate invasive cell-on-cell migration in Drosophila.',PLoS ONEhttp://europepmc.org/articles/PMC3396602?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
These glia responses led to a noticeable increase of neuron–glia approximations.
Nicole Rosskothen-Kuhl, Heika Hildebrandt, Ralf Birkenhäger, Robert-Benjamin Illing 2018, 'Astrocyte Hypertrophy and Microglia Activation in the Rat Auditory Midbrain Is Inducedby Electrical Intracochlear Stimulation', Frontiers in Cellular Neurosciencehttp://journal.frontiersin.org/article/10.3389/fncel.2018.00043/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Here we review the structural and functional characterization of such extracellular vesicles in neuron-glia interactions.
Manuela eBasso, Valentina eBonetto 2016, 'Extracellular vesicles and a novel form of communication in the brain', Frontiers in Neurosciencehttp://journal.frontiersin.org/Journal/10.3389/fnins.2016.00127/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Twenty antibodies directed against antigens specific to neurons, synapses and glia were used.
Stephenson Diane T, O'Neill Sharon M, Narayan Sapna, Tiwari Aadhya, Arnold Elizabeth,Samaroo Harry D, Du Fu, Ring Robert H, Campbell Brian, Pletcher Mathew, Vaidya ViditaA, Morton Daniel 2011, 'Histopathologic characterization of the BTBR mouse model of autistic-like behaviorreveals selective changes in neurodevelopmental proteins and adult hippocampal neurogenesis',Molecular Autismhttp://www.molecularautism.com/content/2/1/7. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
None of them induced expression in glia or in nondopaminergic neurons in striatum or cortex.
Anne-Sophie Rolland, Tatyana Kareva, Olga Yarygina, Nikolai Kholodilov, Robert E Burke 2016, 'Expression mediated by three partial sequences of the human tyrosine hydroxylase promoterin vivo', Molecular Therapy: Methods & Clinical Developmenthttp://www.sciencedirect.com/science/article/pii/S2329050116301905. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Epifluorescence imaging of dissociated retinal cultures 24 hours after infection indicated preferential infection of glia.
João M Furtado, Liam M Ashander, Kathleen Mohs, Timothy J Chipps, Binoy Appukuttan,Justine R Smith 2013, 'Toxoplasma gondii migration within and infection of human retina.', PLoS ONEhttp://europepmc.org/articles/PMC3578837?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)