(ˌfiːnəʊˈbɑːbɪtəl) or phenobarbitone (ˈfiːnəʊˈbɑːbɪtəʊn)
noun
a white crystalline derivative of barbituric acid used as a sedative for treating insomnia and as an anticonvulsant in epilepsy. Formula: C12H12N2O3
Examples of 'phenobarbitone' in a sentence
phenobarbitone
Repeated laboratory evaluation demonstrated toxic levels of phenobarbitone in his blood.
Sankalp Gokhale, Ciro Ramos-Estebanez 2013, 'An Interesting Case of Barbiturate Automatism and Review of Literature', Case Reports in Neurological Medicinehttp://dx.doi.org/10.1155/2013/713065. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The fabricated sensors showed high selectivity for phenobarbitone over the investigated foreign species.
Alrabiah Haitham, Al-Majed Abdulrahman, Abounassif Mohammed, Mostafa Gamal A.E. 2016, 'Ionophore-based potentiometric PVC membrane sensors for determination of phenobarbitonein pharmaceutical formulations', Acta Pharmaceuticahttp://www.degruyter.com/view/j/acph.2016.66.issue-4/acph-2016-0042/acph-2016-0042.xml?format=INT. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
His seizures were well controlled on phenobarbitone for years.
Sankalp Gokhale, Ciro Ramos-Estebanez 2013, 'An Interesting Case of Barbiturate Automatism and Review of Literature', Case Reports in Neurological Medicinehttp://dx.doi.org/10.1155/2013/713065. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Patch tests were carried out in twenty patients and ten controls with carbamazepine, phenytoin sodium, phenobarbitone and sodium valproate.
Vatve Maneesha, Sharma Vinod, Sawhney IMS, Kumar Bhushan 2000, 'Evaluation of patch test in identification of causative agent in drug rashes due toantiepileptics', Indian Journal of Dermatology, Venereology and Leprologyhttp://www.ijdvl.com/article.asp?issn=0378-6323;year=2000;volume=66;issue=3;spage=132;epage=135;aulast=Vatve. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We discuss the most frequent predisponent factors, and their relationship with chronic use of anticonvulsants, particularly phenobarbitone.
PATRÍCIA CORAL, ALESSANDRA ZANATTA, HÉLIO A. G. TEIVE, YLMAR CORREA NETO, EDISON MATOSNÓVAK, LINEU CÉSAR WERNECK 1999, 'Doenças de Dupuytren e de Ledderhose associadas ao uso crônico de anticonvulsivantes:relato de caso Dupuytren's and Ledderhose's diseases associated with chronic use ofanticonvulsants: case report', Arquivos de Neuro-Psiquiatriahttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1999000500020. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Skeletal muscle relaxant effect was evaluated by using rotarod apparatus and sedative potentiating property by phenobarbitone-induced sleep potentiation study.
Protapaditya Dey, Sangita Chandra, Priyanka Chatterjee, Sanjib Bhattacharya 2011, 'Neuropharmacological properties of Mikania scandens (L.) Willd. (Asteraceae)', Journal of Advanced Pharmaceutical Technology & Researchhttp://www.japtr.org/article.asp?issn=2231-4040;year=2011;volume=2;issue=4;spage=255;epage=259;aulast=Dey. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
It was treated with cooling, intravenous fluid, and phenobarbitone administration which was later changed to levetiracetam.
Carl Adagra, Susan Amanda Piripi 2014, 'Hippocampal Necrosis in a Cat from Australia', Case Reports in Veterinary Medicinehttp://dx.doi.org/10.1155/2014/306789. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
He was initially placed on sodium valproate and phenobarbitone and later had phenobarbitonereplaced with levetiracetam.
Orakwue A. Molokwu, Birinus A. Ezeala-Adikaibe, Ikenna O. Onwuekwe 2015, 'Levetiracetam-induced rage and suicidality: Two case reports and review of literature',Epilepsy and Behavior Case Reportshttp://www.sciencedirect.com/science/article/pii/S221332321500033X. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)