[1895–1900; glyco- + -lytic]This word is first recorded in the period 1895–1900. Other words that entered Englishat around the same time include: Marxism, calling card, cutback, freewheel, slapstickglyco- is a combining form with the meanings “sugar,” “glucose and its derivatives,” usedin the formation of compound words. Other words that use the affix glyco- include: glycogen, glycogenetic, glyconeogenesis, glycoprotein, glycosaminoglycan; -lytic is a combining form occurring in adjectives that correspond to nouns ending in -lysis. Other words that use the affix -lytic include: analytic, paralytic
Examples of 'glycolytic' in a sentence
glycolytic
Alterations in glycolytic pathway activation were required for the anti-inflammatory effect of ouabain.
Chao Shao, Shengwei Lin, Sudan Liu, Peipei Jin, Wenbin Lu, Na Li, Yan Zhang, LulongBo, Jinjun Bian 2019, 'HIF1α-Induced Glycolysis in Macrophage Is Essential for the Protective Effect of Ouabainduring Endotoxemia', Oxidative Medicine and Cellular Longevityhttp://dx.doi.org/10.1155/2019/7136585. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Most prominent was a general reduction in abundance of enzymes in the glycolytic pathway.
Lloyd Berger, Andrew Wilde 2013, 'Glycolytic metabolites are critical modulators of oocyte maturation and viability.',PLoS ONEhttp://europepmc.org/articles/PMC3805577?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We show that this conversion occurs only in the presence of glycolytic carbon sources.
Selma S Alkafeef, Clinton Yu, Lan Huang, Haoping Liu 2018, 'Wor1 establishes opaque cell fate through inhibition of the general co-repressor Tup1in Candida albicans.', PLoS Geneticshttp://europepmc.org/articles/PMC5786334?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Glucose consumption, metabolite efflux and gene expression of glycolytic and lipogenesis-related genes were measured.
Floriana Rotondo, Ana Cecilia Ho-Palma, Xavier Remesar, José Antonio Fernández-López,María del Mar Romero, Marià Alemany 2018, 'Effect of sex on glucose handling by adipocytes isolated from rat subcutaneous, mesentericand perigonadal adipose tissue', PeerJhttps://peerj.com/articles/5440.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
M1 macrophages use glycolytic metabolism to optimize oxygen consumption and activate myofibroblasts and fibrocytes.
Tarcio Teodoro Braga, Juan Sebastian Henao, Niels Olsen Saraiva Camara, Niels OlsenSaraiva Camara, Niels Olsen Saraiva Camara 2015, 'Macrophages during the fibrotic process: M2 as friend and foe.', Frontiers in Immunologyhttp://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00602/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Much lower glycolytic rates have been reported in quiescent compared with proliferating lymphocytes.
Johanna M S Lemons, Xiao-Jiang Feng, Bryson D Bennett, Aster Legesse-Miller, ElizabethL Johnson, Irene Raitman, Elizabeth A Pollina, Herschel A Rabitz, Joshua D Rabinowitz,Hilary A Coller 2010, 'Quiescent fibroblasts exhibit high metabolic activity.', PLoS Biologyhttp://europepmc.org/articles/PMC2958657?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In several organisms, enolases have been shown to have diverse non glycolytic (moonlighting) biological functions.
Jarori Gotam K, Vora Hardeep K, Pal-Bhowmick Ipsita 2007, 'Sub-cellular localization and post-translational modifications of the Plasmodiumyoelii enolase suggest moonlighting functions', Malaria Journalhttp://www.malariajournal.com/content/6/1/45. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The glycolytic pathway consists of ten enzymatic steps which appear to be universal amongst eukaryotes.
Silberman Jeffrey D, Baumgartner Manuela, Stechmann Alexandra, Roger Andrew J 2006, 'The glycolytic pathway of Trimastix pyriformis is an evolutionary mosaic',BMC Evolutionary Biologyhttp://www.biomedcentral.com/1471-2148/6/101. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Furthermore, pro-inflammatory cytokines and glycolytic pathways co-regulate each other.
Matija Hedl, Jie Yan, Clara Abraham 2016, 'IRF5 and IRF5 Disease-Risk Variants Increase Glycolysis and Human M1 Macrophage Polarizationby Regulating Proximal Signaling and Akt2 Activation', Cell Reportshttp://www.sciencedirect.com/science/article/pii/S2211124716309913. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)