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单词 spectrin
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spectrin

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spectrin in British English

(ˈspɛktrɪn)
noun
any one of a class of fibrous proteins found in the membranes of red blood cells, the brain, the intestine, etc
Word origin
C20: from spectr(e) + -in, referring to the ghosts (isolated cell membranes) of red blood cells, the sourceof the first known member of the class

spectrin in American English

(ˈspektrɪn)
noun
Biochemistry
a rodlike structural protein of the red blood cell membrane
Word origin
[1968; spect(e)r (cf. ghost def. 12) + -in2]-in is a noun suffix used in a special manner in chemical and mineralogical nomenclature(glycerin; acetin, etc.). In spelling, usage wavers between -in and -ine. In chemistry a certain distinction of use is attempted, basic substances havingthe termination -ine rather than -in (aconitine; aniline, etc.), and -in being restricted to certain neutral compounds, glycerides, glucosides, and proteids(albumin; palmitin, etc.), but this distinction is not always observed

Examples of 'spectrin' in a sentence
spectrin

Besides spectrin, other membrane-skeletal components decrease with cell age.
Annarita Ciana, Cesare Achilli, Giampaolo Minetti 2017, 'Spectrin and Other Membrane-Skeletal Components in Human Red Blood Cells of DifferentAge', Cellular Physiology and Biochemistryhttp://www.karger.com/Article/FullText/478769. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In this study, the nanostructure of the spectrin network was recorded by atomic force microscopy.
Elena Kozlova, Aleksandr Chernysh, Viktoria Sergunova, Ekaterina Manchenko, ViktorMoroz, Aleksandr Kozlov 2019, 'Conformational Distortions of the Red Blood Cell Spectrin Matrix Nanostructure inResponse to Temperature Changes In Vitro', Scanninghttp://dx.doi.org/10.1155/2019/8218912. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In addition, novel markers such as spectrin breakdown product, c-tau and amiloid-b are presented.
Primož Gradišek, Joško Osredkar, Boriana Kremžar, Marjan Koršič 2011, 'Biochemical markers of traumatic brain injury', Zdravniški Vestnikhttp://vestnik.szd.si/index.php/ZdravVest/article/view/127. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The cytoskeleton consists of spectrin tetramers that are tethered to the lipid bilayer by ankyrin and by actin-based junctional complexes.
Thomas G Fai, Alejandra Leo-Macias, David L Stokes, Charles S Peskin 2017, 'Image-based model of the spectrin cytoskeleton for red blood cell simulation.', PLoS Computational Biologyhttp://europepmc.org/articles/PMC5654263?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The folded erythroid spectrin and non-erythroid spectrin were directly converted to unfolded monomer without formation of any intermediate.
Malay Patra, Chaitali Mukhopadhyay, Abhijit Chakrabarti 2015, 'Probing Conformational Stability and Dynamics of Erythroid and Nonerythroid Spectrin:Effects of Urea and Guanidine Hydrochloride', PLOS ONE10.1371/journal.pone.0116991. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
An induction in calpain activity was demonstrated by an increase in the formation of calpain spectrin breakdown products.
Jirapa Chetsawang, Sujira Mukda, Rachneekorn Srimokra, Piyarat Govitrapong, BanthitChetsawang 2017, 'Role of Melatonin in Reducing Amphetamine-Induced Degeneration in Substantia Nigraof Rats via Calpain and Calpastatin Interaction', Journal of Experimental Neurosciencehttps://doi.org/10.1177/1179069517719237. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We report here a new mutation in the ß-spectrin gene coding region in a patient with hereditary spherocytosis.
D.S. Bassères, A.C. Tavares, F.F. Costa, S.T.O. Saad 2002, 'ß-Spectrin São PauloII, a novel frameshift mutation of the ß-spectrin gene associatedwith hereditary spherocytosis and instability of the mutant mRNA', Brazilian Journal of Medical and Biological Researchhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000800009. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The earliest changes, such as elevated spectrin breakdown and amyloid-β levels, may make retinal ganglion cells susceptible to future stressors.
Gina Nicole Wilson, Gina Nicole Wilson, Matthew Alan Smith, Denise M Inman, ChristineM Dengler-Crish, Samuel David Crish 2016, 'Early cytoskeletal protein modifications precede overt structural degeneration inthe DBA/2J mouse model of glaucoma', Frontiers in Neurosciencehttp://journal.frontiersin.org/Journal/10.3389/fnins.2016.00494/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Molecular modelling studies of spectrin suggest that a sugar moiety can fit into the potential glycosylation sites.
Sajal Samanta, Devawati Dutta, Angana Ghoshal, Sumi Mukhopadhyay, Bibhuti Saha, ShyamSundar, Saulius Jarmalavicius, Michael Forgber, Chhabinath Mandal, Peter Walden, ChitraMandal 2011, 'Glycosylation of erythrocyte spectrin and its modification in visceral leishmaniasis.',PLoS ONEhttp://europepmc.org/articles/PMC3229537?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Spectrin alpha chain, band 3 protein, glyceraldehyde-3-phosphate dehydrogenase, and ankyrin-1 were the main proteins affected by storage.
Amna Mohamed Al-Thani, Sven Christian Voss, Afnan Saleh Al-Menhali, Andrei Barcaru,Peter Horvatovich, Hind Al Jaber, Zoran Nikolovski, Aishah Latiff, Costas Georgakopoulos,Zeyd Merenkov, Jordi Segura, Mohammed Alsayrafi, Morana Jaganjac 2018, 'Whole Blood Storage in CPDA1 Blood Bags Alters Erythrocyte Membrane Proteome', Oxidative Medicine and Cellular Longevityhttp://dx.doi.org/10.1155/2018/6375379. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
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更新时间：2024/12/22 17:03:31