any of a class of phospholipids occurring in biological membranes and fats
Examples of 'phosphatidylserine' in a sentence
phosphatidylserine
Phosphatidylserine exposure could be inhibited by addition of erythropoietin.
Elisabeth Lang, Vitaly I. Pozdeev, Haifeng C. Xu, Prashant V. Shinde, Kristina Behnke,Junnat M. Hamdam, Erik Lehnert, Rüdiger E. Scharf, Florian Lang, Dieter Häussinger,Karl S. Lang, Philipp A. Lang 2016, 'Storage of Erythrocytes Induces Suicidal Erythrocyte Death', Cellular Physiology and Biochemistryhttp://www.karger.com/Article/FullText/445657. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The model membranes contained liquid-ordered regions or phosphatidylserine.
Teresa Janas, Karolina Sapoń, Michael H. B. Stowell, Tadeusz Janas 2019, 'Selection of Membrane RNA Aptamers to Amyloid Beta Peptide: Implications for Exosome-BasedAntioxidant Strategies', International Journal of Molecular Scienceshttp://www.mdpi.com/1422-0067/20/2/299. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Endothelial cells that are not confluent expose phosphatidylserine and therefore mimic the tumor vasculature.
John J Krais, Olivier De Crescenzo, Roger G Harrison 2013, 'Purine nucleoside phosphorylase targeted by annexin v to breast cancer vasculaturefor enzyme prodrug therapy.', PLoS ONEhttp://europepmc.org/articles/PMC3789731?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Histones induced phosphatidylserine and protein-disulfide isomerase expression in endothelial cells.
Ji Eun Kim, Hyun Ju Yoo, Ja Yoon Gu, Hyun Kyung Kim 2016, 'Histones Induce the Procoagulant Phenotype of Endothelial Cells through Tissue FactorUp-Regulation and Thrombomodulin Down-Regulation.', PLoS ONEhttp://europepmc.org/articles/PMC4892514?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Additional markers of apoptosis were also measured like phosphatidylserine externalization and morphological changes.
Xue-Mei Gong, Cheng-Jiu Hu, Quan-Jing Zhao, Dong-Mei Shi 2015, 'Equol induces apoptosis in chemoresistant ovarian cancer cells via external pathway',Bangladesh Journal of Pharmacologyhttps://www.banglajol.info/index.php/BJP/article/view/23835. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In vitro studies showed cell membrane damage without exposure of phosphatidylserine, an early apoptosis hallmark.
Silvia Posada Arias, Paola Rey-Suárez, Andrés Pereáñez J, Cristian Acosta, MauricioRojas, Lucilene Delazari dos Santos, Rui Seabra Ferreira Jr, Vitelbina Núñez 2017, 'Isolation and Functional Characterization of an Acidic Myotoxic Phospholipase A2 fromColombian Bothrops asper Venom', Toxinshttps://www.mdpi.com/2072-6651/9/11/342. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The transbilayer movement of phosphatidylserine mediates the platelet procoagulant activity during collagen stimulation.
Swapan K Dasgupta, Anhquyen Le, Sandra B Haudek, Mark L Entman, Rolando E Rumbaut,Perumal Thiagarajan 2013, 'Rho associated coiled-coil kinase-1 regulates collagen-induced phosphatidylserineexposure in platelets.', PLoS ONEhttp://europepmc.org/articles/PMC3865301?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
These included phospholipids with pleiotropic brain function, such as derivatives of phosphatidylcholine, phosphatidylserine, and phosphatidylethanolamine.
Roman Šmidák, Harald C Köfeler, Harald Hoeger, Gert Lubec 2017, 'Comprehensive identification of age-related lipidome changes in rat amygdala duringnormal aging.', PLoS ONEhttp://europepmc.org/articles/PMC5495493?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Ca2+ levels required to elicit phosphatidylserine exposure were in the low micromolar range.
Erwin Weiss, David Charles Rees, John Stanley Gibson 2011, 'Role of Calcium in Phosphatidylserine Externalisation in Red Blood Cells from SickleCell Patients', Anemiahttp://dx.doi.org/10.1155/2011/379894. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Flow cytometry was used to investigate mitochondrial dysfunction and phosphatidylserine exposure.
Amanda Louzano Moreira, Débora Botura Scariot, Bruna Luíza Pelegrini, Greisiele LorenaPessini, Tânia Ueda-Nakamura, Celso Vataru Nakamura, Izabel Cristina Piloto Ferreira 2017, 'Acyclic Sesquiterpenes from the Fruit Pericarp of Sapindus saponaria Induce UltrastructuralAlterations and Cell Death in Leishmania amazonensis', Evidence-Based Complementary and Alternative Medicinehttp://dx.doi.org/10.1155/2017/5620693. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)