any of a class of compounds some of which are used in the treatment of certain formsof diabetes
See also phenformin
Word origin
C19: from bi-1 + guanidine + -ide
Examples of 'biguanide' in a sentence
biguanide
Recently, metformin, the most widely prescribed biguanide, has emerged as a potential anticancer agent.
Goodwin Pamela J, Dowling Ryan JO, Stambolic Vuk 2011, 'Understanding the benefit of metformin use in cancer treatment', BMC Medicinehttp://www.biomedcentral.com/1741-7015/9/33. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Sodium hypochlorite was the most effective disinfectant against biofilm cells, while biguanide was the least effective.
Tatiane Karen Cabeça, Antonio Carlos Pizzolitto, Elisabeth Loshchagin Pizzolitto 2012, 'Activity of disinfectants against foodborne pathogens in suspension and adhered tostainless steel surfaces', Brazilian Journal of Microbiologyhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822012000300038. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Although the biguanide resulted in significant decimal reduction, none of the sanitizing agents studied was effective under the evaluated conditions.
Edite Andrade Costa, Leonardo Justino Carioca, Valdeir Viana Freitas, Maurilio LopesMartins, Aurélia Dornelas de Oliveira Martins, Cláudia Lúcia de Oliveira Pinto 2017, 'Evaluation of sanitizers efficiency over spore forming bacteria isolated from wholeUHT milk', Revista do Instituto de Latícinios Cândido Tosteshttps://www.revistadoilct.com.br/rilct/article/view/442. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The biguanide-antifungal combinations allowed for additional antifungal effects, with fraction inhibition concentration indexes ranging from 0.5 to 1.
Shuying Xu, Marianela Feliu, Allison K. Lord, Daniel P. Lukason, Paige E. Negoro,Nida S. Khan, Zeina Dagher, Michael B. Feldman, Jennifer L. Reedy, Samantha N. Steiger,Jenny M. Tam, Alexander A. Soukas, David B. Sykes, Michael K. Mansour 2018, 'Biguanides enhance antifungal activity against Candida glabrata', Virulencehttp://dx.doi.org/10.1080/21505594.2018.1475798. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)