Herein, we describe the development of a three-step route from inexpensive and commercially available picolinic acid.
Hideki Shimizu, Jeffrey C. Holder, Brian M. Stoltz 2013, 'A scalable synthesis of the (S)-4-(tert-butyl)-2-(pyridin-2-yl)-4,5-dihydrooxazole((S)-t-BuPyOx) ligand', Beilstein Journal of Organic Chemistryhttps://doi.org/10.3762/bjoc.9.187. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)