Splenium infarctions were often associated with bilateral cerebral hemisphere involvement (46.2%).
Shen Li, Xin Sun, Yu-meng Bai, Hua-min Qin, Xiao-mei Wu, Xiao Zhang, Jukka Jolkkonen,Johannes Boltze, Su-ping Wang 2015, 'Infarction of the corpus callosum: a retrospective clinical investigation.', PLoS ONEhttp://europepmc.org/articles/PMC4364734?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
All the cases had noncontiguous involvement of the splenium.
Hardeep Singh Malhotra, Ravindra Kumar Garg, Mukund R Vidhate, Pawan Kumar Sharma 2012, 'Boomerang sign: Clinical significance of transient lesion in splenium of corpus callosum',Annals of Indian Academy of Neurologyhttp://www.annalsofian.org/article.asp?issn=0972-2327;year=2012;volume=15;issue=2;spage=151;epage=157;aulast=Malhotra. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Two months later, the hyperintense lesions in the splenium and the basal ganglia had disappeared.
Alena Meleková, Leona Andrlová, Pavel Král, Leoš Ungermann, Edvard Ehler 2015, 'Encephalitis with Prolonged but Reversible Splenial Lesion', Acta Medicahttp://actamedica.lfhk.cuni.cz/58/3/0108/. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The most susceptible location of ischemic corpus callosum lesion was the splenium.
Shen Li, Xin Sun, Yu-meng Bai, Hua-min Qin, Xiao-mei Wu, Xiao Zhang, Jukka Jolkkonen,Johannes Boltze, Su-ping Wang 2015, 'Infarction of the corpus callosum: a retrospective clinical investigation.', PLoS ONEhttp://europepmc.org/articles/PMC4364734?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Thirty six patients had lesions in the splenium (61.0%).
Shen Li, Xin Sun, Yu-meng Bai, Hua-min Qin, Xiao-mei Wu, Xiao Zhang, Jukka Jolkkonen,Johannes Boltze, Su-ping Wang 2015, 'Infarction of the corpus callosum: a retrospective clinical investigation.', PLoS ONEhttp://europepmc.org/articles/PMC4364734?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Brain magnetic resonance imaging revealed an ovoid lesion in the splenium of the corpus callosum.
Olcay Ünver, Büşra Kutlubay, Tolga Besci, Gazanfer Ekinci, Feyyaz Baltacıoğlu, DilşadTürkdoğan 2016, 'Transient Splenial Lesion of the Corpus Callosum Related to Migraine with Aura ina Pediatric Patient', Acta Medicahttp://actamedica.lfhk.cuni.cz/59/2/0064/. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Transient splenium lesions may develop in association with various pathologies and infections.
Mucahit Gunaydin, Faruk Ozsahin 2018, 'Transient visual loss: Transient lesion in the splenium of the corpus callosum', Turkish Journal of Emergency Medicinehttp://www.sciencedirect.com/science/article/pii/S2452247317302273. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The splenium was the most frequent site (37.5%).
Zhiyong Zhang, Xiufeng Meng, Wei Liu, Zunjing Liu 2019, 'Clinical Features, Etiology, and 6-Month Prognosis of Isolated Corpus Callosum Infarction',BioMed Research Internationalhttp://dx.doi.org/10.1155/2019/9458039. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)