a drug, C10H22N4, that is used to reduce high blood pressure
guanethidine in American English
(ɡwɑnˈeθɪˌdin)
noun
Pharmacology
a potent adrenergic neuron blocking agent, C10H22N4, used in the treatment of hypertension
Word origin
[1955–60; by insertion of eth(yl) into guanidine]This word is first recorded in the period 1955–60. Other words that entered Englishat around the same time include: backgrounder, cassette, new wave, rite of passage, software
Examples of 'guanethidine' in a sentence
guanethidine
The contractions were abolished by previous incubation with either phentolamine or guanethidine.
Rafael Campos, Fabíola Z Mónica, Renata Lopes Rodrigues, Julio Alejandro Rojas-Moscoso,Ronilson Agnaldo Moreno, José Carlos Cogo, Marco Antonio de Oliveira, Edson Antunes,Gilberto De Nucci 2017, 'Tetrodotoxin-insensitive electrical field stimulation-induced contractions on Crotalusdurissus terrificus corpus cavernosum.', PLoS ONEhttp://europepmc.org/articles/PMC5570490?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The guanethidine/-adrenaline formulation was found to be the more effective hypotensive agent of two.
Mehrotra A, Jain B, Anand G 1987, 'Comparative evaluation of pilocarpine 2% and combined guanethidine 1%& adrenaline 0.5% in the treatment of chronic simple glaucoma', Indian Journal of Ophthalmologyhttp://www.ijo.in/article.asp?issn=0301-4738;year=1987;volume=35;issue=3;spage=146;epage=148;aulast=Mehrotra. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Intravenous systemic regional blockade with guanethidine has been shown to be without effect.
McQuay, Moore, Eccleston, Morley, Williams 1997, 'Systematic review of outpatient services for chronic pain control.', Health Technology Assessmenthttps://doi.org/10.3310/hta1060. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The experimental results show measurable anti-influenza activity of guanethidine in cell culture.
Draginja Radosevic, Milan Sencanski, Vladimir Perovic, Nevena Veljkovic, Jelena Prljic,Veljko Veljkovic, Emily Mantlo, Natalya Bukreyeva, Slobodan Paessler, Slobodan Paessler,Sanja Glisic 2019, 'Virtual Screen for Repurposing of Drugs for Candidate Influenza a M2 Ion-Channel Inhibitors',Frontiers in Cellular and Infection Microbiologyhttps://www.frontiersin.org/article/10.3389/fcimb.2019.00067/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)