a substance formed in the blood, as by bacterial action, that causes the destruction of red corpuscles with liberation of hemoglobin
Word origin
< hemo- + Gr lysis, a dissolving + -in1
hemolysin in American English
(hɪˈmɑlɪsɪn, ˌhiməˈlai-, ˌhemə-)
noun
Immunology
a substance, as an antibody, that in cooperation with complement causes dissolution of red blood cells
Word origin
[1895–1900; hemo- + lysin]This word is first recorded in the period 1895–1900. Other words that entered Englishat around the same time include: Marxism, calling card, cutback, frame of reference, neonhemo- is a combining form meaning “blood,” used in the formation of compound words. Otherwords that use the affix hemo- include: hemochrome, hemodialysis, hemodynamics, hemosiderin, hemostatic
Examples of 'hemolysin' in a sentence
hemolysin
Such a multivalent vaccine may include attenuated leukotoxins, alpha hemolysin, and superantigens.
Hatice Karauzum, Rajan P. Adhikari, Jawad Sarwar, V. Sathya Devi, Laura Abaandou,Christian Haudenschild, Mahta Mahmoudieh, Atefeh R. Boroun, Hong Vu, Tam Nguyen, KellyL. Warfield, Sergey Shulenin, M. Javad Aman 2013, 'Structurally Designed Attenuated Subunit Vaccines for S. aureus LukS-PV and LukF-PVConfer Protection in a Mouse Bacteremia Model', PLoS ONE10.1371/journal.pone.0065384. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Mass spectrometric analysis revealed the capture by liposomes of phenol-soluble modulins, α-hemolysin and other toxins.
Heidi Wolfmeier, Sarah C. Mansour, Leo T. Liu, Daniel Pletzer, Annette Draeger, EduardB. Babiychuk, Robert E.W. Hancock 2018, 'Liposomal Therapy Attenuates Dermonecrosis Induced by Community-Associated Methicillin-ResistantStaphylococcus aureus by Targeting α-Type Phenol-Soluble Modulins and α-Hemolysin',EBioMedicinehttp://www.sciencedirect.com/science/article/pii/S2352396418302238. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Vesicles successfully incorporate the integral membrane protein α-hemolysin and maintain its membrane transport function.
M. Gertrude Gutierrez, Shotaro Yoshida, Noah Malmstadt, Shoji Takeuchi 2018, 'Photolithographic patterned surface forms size-controlled lipid vesicles', APL Bioengineeringhttp://dx.doi.org/10.1063/1.5002604. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The identified antigens included a number of putative membrane proteins, lipoproteins, and hemolysin-related proteins.
Richelle C Charles, Tania Sultana, Mohammad Murshid Alam, Yanan Yu, Ying Wu-Freeman,Meagan Kelly Bufano, Sean M Rollins, Lillian Tsai, Jason B Harris, Regina C LaRocque,Daniel T Leung, W Abdullah Brooks, Tran Vu Thieu Nga, Sabina Dongol, Buddha Basnyat,Stephen B Calderwood, Jeremy Farrar, Farhana Khanam, John S Gunn, Firdausi Qadri,Stephen Baker, Edward T Ryan 2013, 'Identification of immunogenic Salmonella enterica serotype Typhi antigens expressedin chronic biliary carriers of S. Typhi in Kathmandu, Nepal.', PLoS Neglected Tropical Diseaseshttp://europepmc.org/articles/PMC3731212?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Transposon insertions in 72 genes resulting in increased or decreased hemolysin expression were identified.
Kellie Burnside, Annalisa Lembo, Melissa de Los Reyes, Anton Iliuk, Nguyen-Thao Binhtran,James E Connelly, Wan-Jung Lin, Byron Z Schmidt, Anthony R Richardson, Ferric C Fang,Weiguo Andy Tao, Lakshmi Rajagopal 2010, 'Regulation of hemolysin expression and virulence of Staphylococcus aureus by a serine/threoninekinase and phosphatase.', PLoS ONEhttp://europepmc.org/articles/PMC2884019?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Genetic and biochemical analysis implicate the biosurfactant serratamolide as a hemolysin.
Robert M Q Shanks, Nicholas A Stella, Roni M Lahr, Shaoru Wang, Tara I Veverka, RegisP Kowalski, Xinyu Liu 2012, 'Serratamolide is a hemolytic factor produced by Serratia marcescens.', PLoS ONEhttp://europepmc.org/articles/PMC3353980?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In total, 10.2% (12 of 118) of the isolates lacked δ-like hemolysin activity.
Chun-Fu Yeh, Tsui-Ping Liu, Chun-Wen Cheng, Shih-Cheng Chang, Ming-Hsun Lee, Jang-JihLu 2015, 'Molecular Characteristics of Disease-Causing and Commensal Staphylococcus lugdunensisIsolates from 2003 to 2013 at a Tertiary Hospital in Taiwan.', PLoS ONEhttp://europepmc.org/articles/PMC4527845?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Thirteen (62.0%) isolates, carrying stx or eae gene, also showed a hemolysin production.
Cleber Jacob Silva de Paula, José Moacir Marin 2008, 'Occurrence of non-O157 Shiga toxin-producing Escherichia coli in dogs with diarrheaOcorrência de Escherichia coli não-O157 Shigatoxigênica em cachorros com diarréia',Ciência Ruralhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782008000600029. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Hemolysin production and biofilm formation were the second most 22 (39%) expressedvirulence factors.
Tapan Majumdar, Jhinuk Basu Mullick, Raunak Bir, Jayanta Roy, Samir Kumar Sil 2016, 'Determination of virulence factors and biofilm formation among isolates of vulvovaginalcandidiasis', Journal of Medical Scienceshttp://jms.ndmctsgh.edu.tw/article.asp?issn=1011-4564;year=2016;volume=36;issue=2;spage=53;epage=58;aulast=Majumdar. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)