nounWord forms: pluralˌhepaˈtomas or ˌhepaˈtomata (ˌhɛpəˈtoʊmətə)
a cancer of the liver or from liver cells
Word origin
hepato- + -oma
hepatoma in American English
(ˌhepəˈtoumə)
nounWord forms: plural-mas or -mata (-mətə)
Pathology
a tumor of the liver
Word origin
[1925–30; hepat- + -oma]This word is first recorded in the period 1925–30. Other words that entered Englishat around the same time include: Nazi, decibel, dropout, runout, turnaround-oma is a noun suffix used to form names of tumors, of the kind specified by the base.Other words that use the affix -oma include: angioma, atheroma, hybridoma, insulinoma, trachoma
Examples of 'hepatoma' in a sentence
hepatoma
Many plant-derived agents have been accepted to effectively inhibit hepatoma cell invasion.
Bing Liu, Genshu Wang, Jie Yang, Xuediao Pan, Zhicheng Yang, Linquan Zang 2011, 'Berberine Inhibits Human Hepatoma Cell Invasion without Cytotoxicity in Healthy Hepatocytes',PLoS ONE10.1371/journal.pone.0021416. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Two novel human hepatoma cell lines were established.
Chih-Lang Lin, Rong-Nan Chien, Shi-Ming Lin, Po-Yuan Ke, Chen-Chun Lin, Chau-TingYeh 2013, 'An occult hepatitis B-derived hepatoma cell line carrying persistent nuclear viralDNA and permissive for exogenous hepatitis B virus infection.', PLoS ONEhttp://europepmc.org/articles/PMC3667124?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In this study, the unique effects of dioscin on autophagy of hepatoma cells were investigated.
Ming-Ju Hsieh, Shun-Fa Yang, Yih-Shou Hsieh, Tzy-Yen Chen, Hui-Ling Chiou 2012, 'Autophagy Inhibition Enhances Apoptosis Induced by Dioscin in Huh7 Cells', Evidence-Based Complementary and Alternative Medicinehttp://dx.doi.org/10.1155/2012/134512. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Hepatoma cells displayed a high level of free radicals compared to immortalized normal hepatocyte cells.
Shi Dong-yun, Xie Fei-zhou, Zhai Chao, Stern Jeremy S, Liu Yang, Liu Shan-lin 2009, 'The role of cellular oxidative stress in regulating glycolysis energy metabolism inhepatoma cells', Molecular Cancerhttp://www.molecular-cancer.com/content/8/1/32. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
A hepatoma had also been noted 2 years previously.
L Yi-Lan, S Wen-Ko, L Yu-Peng 2011, 'Duodenal varices', Journal of the Belgian Society of Radiologyhttps://www.jbsr.be/articles/506. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In conclusion, inhibition of autophagy could enhance matrine-induced apoptosis in human hepatoma cells.
Li Wang, Chun Gao, Shukun Yao, Bushan Xie 2013, 'Blocking Autophagic Flux Enhances Matrine-Induced Apoptosis in Human Hepatoma Cells',International Journal of Molecular Scienceshttp://www.mdpi.com/1422-0067/14/12/23212. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Most patients (73%) had underlying malignancy, most often hepatoma (45%).
Liang-Wen Ding, Chih-Cheng Lai, Li-Na Lee, Po-Ren Hsueh 2006, 'Abdominal Nontuberculous Mycobacterial Infection in a University Hospital in Taiwanfrom 1997 to 2003', Journal of the Formosan Medical Associationhttp://www.sciencedirect.com/science/article/pii/S0929664609601327. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Uptake of fluorescent-labeled exosomes by hepatoma recipient cells was monitored by confocal microscopy.
Fabia Fricke, Jennifer Lee, Malwina Michalak, Uwe Warnken, Ingrid Hausser, Meggy Suarez-Carmona,Niels Halama, Martina Schnölzer, Jürgen Kopitz, Johannes Gebert 2017, 'TGFBR2-dependent alterations of exosomal cargo and functions in DNA mismatch repair-deficientHCT116 colorectal cancer cells', Cell Communication and Signalinghttp://link.springer.com/article/10.1186/s12964-017-0169-y. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Y134 also induced apoptosis in hepatoma cells without having an effect on cell cycle regulation.
Hyo Sang Jang, Martin Pearce, Edmond F. O'Donnell, Bach Duc Nguyen, Lisa Truong, MonicaJ. Mueller, William H. Bisson, Nancy I. Kerkvliet, Robert L. Tanguay, Siva Kumar Kolluri 2017, 'Identification of a Raloxifene Analog That Promotes AhR-Mediated Apoptosis in CancerCells', Biologyhttps://www.mdpi.com/2079-7737/6/4/41. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
It was also the case in cytospins from human hepatoma cell line.
Wojciech Służewski, Jan Sikora, Elżbieta Kaczmarek, Husam Samara, Renata Jenek, AnnaMania, Arleta Kowala-Piaskowska, Iwona Mozer-Lisewska, Jan Żeromski 2011, 'Expression of pattern recognition receptors in liver biopsy specimens of childrenchronically infected with HBV and HCV', Folia Histochemica et Cytobiologicahttp://czasopisma.viamedica.pl/fhc/article/view/9434. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)