Unambiguous stereochemical assignments of both diastereomeric series are reported.
Faiz Ahmed Khan, Karuppasamy Parasuraman 2010, 'Synthesis of oxa-bridged derivatives from Diels–Alder bis-adducts of butadiene and1,2,3,4-tetrahalo-5,5-dimethoxycyclopentadiene', Beilstein Journal of Organic Chemistryhttps://doi.org/10.3762/bjoc.6.64. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The generated model was carefully evaluated for stereochemical accuracy, folding correctness and overall structure quality.
Mohamed A. Abdallah Elbadawi, Mohamed Khalid Alhaj Awadalla, Muzamil Mahdi Abdel Hamid,Magdi Awadalla Mohamed, Talal Ahmed Awad 2015, 'Valproic Acid as a Potential Inhibitor of Plasmodium falciparum Histone Deacetylase1 (PfHDAC1): An in Silico Approach', International Journal of Molecular Scienceshttp://www.mdpi.com/1422-0067/16/2/3915. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Z-scores and other stereochemical features were estimated for comparison.
Arundhati Banerjee, Sujay Ray 2016, 'Structural Exploration and Conformational Transitions in MDM2 upon DHFR Interactionfrom Homo sapiens: A Computational Outlook for Malignancy via Epigenetic Disruption',Scientificahttp://dx.doi.org/10.1155/2016/9420692. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The designed compounds were of high purity, low polydispersity and high stereochemical purity.
Gáborjányi R, Almás M, Pál K, Tyihá E, Szökán Gy, Szende B, Khlafulla A R 2002, 'Antitumor effect of lysine-isopeptides', Cancer Cell Internationalhttp://www.cancerci.com/content/2/1/4. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The rate of stereochemical conversion decreased with age.
Joske Millecam, Thomas van Bergen, Stijn Schauvliege, Gunther Antonissen, Ann Martens,Koen Chiers, Ronette Gehring, Elke Gasthuys, Johan Vande Walle, Siska Croubels, MathiasDevreese 2019, 'Developmental Pharmacokinetics and Safety of Ibuprofen and Its Enantiomers in theConventional Pig as Potential Pediatric Animal Model', Frontiers in Pharmacologyhttps://www.frontiersin.org/article/10.3389/fphar.2019.00505/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The fused tricyclic products are formed with complete or very high stereochemical control.
Iain Coldham, Adam J. M. Burrell, Hélène D. S. Guerrand, Luke Watson, Nathaniel G.Martin, Niall Oram 2012, 'Synthesis of fused tricyclic amines unsubstituted at the ring-junction positions bya cascade condensation, cyclization, cycloaddition then decarbonylation strategy',Beilstein Journal of Organic Chemistryhttps://doi.org/10.3762/bjoc.8.11. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
This review centered on stereochemical aspects of the hydrobenzofuran type, a widespread skeleton among neolignans.
Massayoshi Yoshida 2012, 'Aspectos estruturais de algumas neolignanas hidrobenzofurânicas', Química Novahttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012001100034&lng=en&tlng=en. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
However, the stereochemical mechanisms responsible for this coupling remain obscure.
Charles R. Midgett, Avinash eGill, Dean R. Madden 2012, 'Domain architecture of a calcium-permeable AMPA receptor in a ligand-free conformation',Frontiers in Molecular Neurosciencehttp://journal.frontiersin.org/Journal/10.3389/fnmol.2011.00056/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The stereochemical outcome of the reactions was established.
Piotr Wałejko, Michał Dąbrowski, Lech Szczepaniak, Jacek W. Morzycki, Stanisław Witkowski 2015, 'Stereochemistry of ring-opening/cross metathesis reactions of exo- and endo-7-oxabicyclo[2.2.1]hept-5-ene-2-carbonitrileswith allyl alcohol and allyl acetate', Beilstein Journal of Organic Chemistryhttps://doi.org/10.3762/bjoc.11.204. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)