relating to or having a fixed position in space, as in the spatial arrangements of atoms in certain polymers
stereospecific in American English
(ˌsteriouspəˈsɪfɪk, ˌstɪər-)
adjective Chemistry
1. (of a reaction)
producing a simple stereoisomer
2. (of a polymer)
having a regular sequence of configurations in space along the chain, resulting in the potential for close-packing of molecules and for partial or complete crystallinity
[stereo- + specific]stereo- is a combining form borrowed from Greek, where it meant “solid”, used with referenceto hardness, solidity, three-dimensionality in the formation of compound words. Otherwords that use the affix stereo- include: stereochemistry, stereogram, stereoscope
Examples of 'stereospecific' in a sentence
stereospecific
The atherogenic potential of palmitic acid and its stereospecific position in triacylglycerols are also discussed.
Annamaria Mancini, Esther Imperlini, Ersilia Nigro, Concetta Montagnese, Aurora Daniele,Stefania Orrù, Pasqualina Buono 2015, 'Biological and Nutritional Properties of Palm Oil and Palmitic Acid: Effects on Health',Moleculeshttp://www.mdpi.com/1420-3049/20/9/17339. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Furthermore, lack of activity of the retro-inverso peptide analogue suggested the involvement of stereospecific recognition.
Carlo Alberto Palmerini, Michela Mazzoni, Giorgia Radicioni, Valeria Marzano, LetiziaGranieri, Federica Iavarone, Renato Longhi, Irene Messana, Tiziana Cabras, Maria TeresaSanna, Massimo Castagnola, Alberto Vitali 2016, 'Antagonistic Effect of a Salivary Proline-Rich Peptide on the Cytosolic Ca2+ MobilizationInduced by Progesterone in Oral Squamous Cancer Cells.', PLoS ONEhttp://europepmc.org/articles/PMC4729474?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
As such, receptors and enzymes are often highly stereospecific, only recognizing one stereoisomer of a ligand.
Amanda L. Garner, Sook Kyung Kim, Jie Zhu, Anjali Kumari Struss, Richard Watkins,Brent D. Feske, Gunnar F. Kaufmann, Kim D. Janda 2012, 'Stereochemical Insignificance Discovered in Acinetobacter baumannii Quorum Sensing',PLoS ONE10.1371/journal.pone.0037102. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
A subgroup of the ectoine producers can convert ectoine into 5-hydroxyectoine through a region-selective and stereospecifichydroxylation reaction.
Nils Widderich, Astrid Höppner, Marco Pittelkow, Johann Heider, Sander H J Smits,Erhard Bremer 2014, 'Biochemical properties of ectoine hydroxylases from extremophiles and their widertaxonomic distribution among microorganisms.', PLoS ONEhttp://europepmc.org/articles/PMC3979721?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The 1,3-dipolar cycloaddition proceeds efficiently under thermal conditions to afford the regio- and stereospecific cyclic adducts.
Manjunatha Narayanarao, Lokesh Koodlur, Vijayakumar G. Revanasiddappa, SubramanyaGopal, Susmita Kamila 2016, 'Multicomponent synthesis of spiropyrrolidine analogues derived from vinylindole/indazoleby a 1,3-dipolar cycloaddition reaction', Beilstein Journal of Organic Chemistryhttps://doi.org/10.3762/bjoc.12.288. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Stereospecific palladium-mediated elimination of allylic acetate provides the target compounds with an excellent enantiomeric excess and yield.
Zeid Abdullah Al-Othman, Yahia Nasser Mabkhot, Assem Barakat, Abdullah M. Al-Majid 2012, 'A Practical Chemo-enzymatic Approach to Highly Enantio-Enriched 10-Ethyl-7,8-dihydro-γ-iononeIsomers: A Method for the Synthesis of 4,5-Didehydro-α-Ionone', International Journal of Molecular Scienceshttp://www.mdpi.com/1422-0067/13/5/5542. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
This paper provides an exhaustive overview of the latest developments in the field of stereospecific polymerization of 1,3-butadiene.
Giovanni Ricci, Giuseppe Leone 1999, 'Recent advances in the polymerization of butadiene over the last decade', Polyolefins Journalhttp://poj.ippi.ac.ir/article_890_4708e0a1a1f4b025ca24d9b0ad1db083.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The described experiments open a pathway for the development of new stereospecific protease inhibitors from a reactive lead compound.
Folasade M. Olajuyigbe, Nicola Demitri, Rita De Zorzi, Silvano Geremia 2016, 'Developing HIV-1 Protease Inhibitors through Stereospecific Reactions in Protein Crystals',Moleculeshttp://www.mdpi.com/1420-3049/21/11/1458. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)