Among these genes, only cyp307a1 has an expression pattern similar to other mosquito steroidogenic genes.
Emilie Pondeville, Jean-Philippe David, Emilie Guittard, Annick Maria, Jean-ClaudeJacques, Hilary Ranson, Catherine Bourgouin, Chantal Dauphin-Villemant 2013, 'Microarray and RNAi Analysis of P450s in Anopheles gambiae Male and Female SteroidogenicTissues: CYP307A1 Is Required for Ecdysteroid Synthesis', PLoS ONE10.1371/journal.pone.0079861. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Follicular density, follicular viability, and steroidogenic capacity were assessed.
Jacira Ribeiro Campos, Julio Cesar Rosa-e-Silva, Bruno Ramalho Carvalho, AlessandraAparecida Vireque, Marcos Felipe Silva-de-Sá, Ana Carolina Japur de Sá Rosa-e-Silva 2011, 'Cryopreservation time does not decrease follicular viability in ovarian tissue frozenfor fertility preservation', Clinicshttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322011001200015. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The steroidogenic capacity of the tissue was not significantly reduced following cryopreservation.
Jacira Ribeiro Campos, Julio Cesar Rosa-e-Silva, Bruno Ramalho Carvalho, AlessandraAparecida Vireque, Marcos Felipe Silva-de-Sá, Ana Carolina Japur de Sá Rosa-e-Silva 2011, 'Cryopreservation time does not decrease follicular viability in ovarian tissue frozenfor fertility preservation', Clinicshttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322011001200015. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The expression of steroidogenic and cholesterol biosynthesis genes was not changed by conazole exposure.
Maarke J.E. Roelofs, A. Roberto Temming, Aldert H. Piersma, Martin van den Berg, MajorieB.M. van Duursen 2014, 'Conazole fungicides inhibit Leydig cell testosterone secretion and androgen receptoractivation in vitro', Toxicology Reportshttp://www.sciencedirect.com/science/article/pii/S2214750014000262. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Electron microscopy revealed typical signs of decreased steroidogenic activity of glomerulosa cells.
Dibakhan A. Tsomartova, Natalia V. Yaglova, Sergey S. Obernikhin, Svetlana V. Nazimova,Valentin V. Yaglov 2018, 'Secretion of adrenal zona glomerulosa cells in rats exposed to low doses of dichlorodiphenyltrichloroethaneduring prenatal and postnatal development', Russian Open Medical Journalhttp://www.romj.org/node/234. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The chronic response results in the increased coordinated transcription of genes encoding steroidogenic enzymes.
Carmen eRuggiero, Enzo eLalli 2016, 'Impact of ACTH signaling on transcriptional regulation of steroidogenic genes', Frontiers in Endocrinologyhttp://journal.frontiersin.org/Journal/10.3389/fendo.2016.00024/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
These are clearly non-steroidogenic actions of these peptides.
Xanthe eVafopoulou, Colin G.H. Steel 2014, 'Synergistic Induction of the Clock Protein PERIOD by Insulin-like Peptide and ProthoracicotropicHormone in Rhodnius prolixus (Hemiptera): Implications for Convergence of HormoneSignalling Pathways', Frontiers in Physiologyhttp://journal.frontiersin.org/Journal/10.3389/fphys.2014.00041/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
These data indicate that dopamine enhances the steroidogenic function of this neuronal progenitor cell.
Lei eXing, Heather eMcDonald, Dillon F Da Fonte, Juan Manuel Gutierrez-Villagomez,Vance eTrudeau 2015, 'Dopamine D1 receptor activation regulates the expression of the estrogen synthesisgene aromatase B in radial glial cell', Frontiers in Neurosciencehttp://journal.frontiersin.org/Journal/10.3389/fnins.2015.00310/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Cell specific expression was also determined in enriched luteal endothelial and steroidogenic cells.
Sigal Kfir, Raghavendra Basavaraja, Noa Wigoda, Shifra Ben-Dor, Irit Orr, Rina Meidan 2018, 'Genomic profiling of bovine corpus luteum maturation.', PLoS ONEhttp://europepmc.org/articles/PMC5874041?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Neurosteroids are steroids made by brain cells independently of peripheral steroidogenic sources.
Geogres eRammouz, Laurent eLecanu, Vassilios ePapadopoulos 2011, 'Oxidative stress-mediated brain dehydroepiandrosterone (DHEA) formation in Alzheimer'sdisease diagnosis', Frontiers in Endocrinologyhttp://journal.frontiersin.org/Journal/10.3389/fendo.2011.00069/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)