The biodegradable ester bonds ensure that the prodrug molecules break down hydrolytically or enzymatically.
Morgan A Clond, Bong-Seop Lee, Jeffrey J Yu, Matthew B Singer, Takayuki Amano, AlexanderW Lamb, Doniel Drazin, Babak Kateb, Eric J Ley, John S Yu 2013, 'Reactive oxygen species-activated nanoprodrug of Ibuprofen for targeting traumaticbrain injury in mice.', PLoS ONEhttp://europepmc.org/articles/PMC3634829?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
However, no obvious difference in shape fixation of dry and physically (hydrolytically) aged samples could be recognized.
Ehsan Ghobadi, Axel Marquardt, Elias Mahmoudinezhad Zirdehi, Klaus Neuking, FathollahVarnik, Gunther Eggeler, Holger Steeb 2018, 'The Influence of Water and Solvent Uptake on Functional Properties of Shape-MemoryPolymers', International Journal of Polymer Sciencehttp://dx.doi.org/10.1155/2018/7819353. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Agaro-oligosaccharides were hydrolytically obtained from agar using hydrochloric acid, citric acid, and cationic exchange resin (solid acid).
Hai-Min Chen, Li Zheng, Xiao-Jun Yan 2005, 'The Preparation and Bioactivity Research of Agaro-Oligosaccharides', Food Technology and Biotechnologyhttp://hrcak.srce.hr/file/162601. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Thermophilic fungi are a promising source of thermostable enzymes able to hydrolytically or oxidatively degrade plant cell wall components.
Marco A. S. Kadowaki, Anikó Várnai, John-Kristian Jameson, Ana E. T. Leite, AntonioJ. Costa-Filho, Patricia S. Kumagai, Rolf A. Prade, Igor Polikarpov, Vincent G. H.Eijsink 2018, 'Functional characterization of a lytic polysaccharide monooxygenase from the thermophilicfungus Myceliophthora thermophila', PLOS ONE10.1371/journal.pone.0202148. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)