any enzyme that catalyzes the introduction of a hydroxyl group into a substance
Word origin
[1950–55; hydroxyl + -ase]This word is first recorded in the period 1950–55. Other words that entered Englishat around the same time include: Common Market, action painting, bleep, drip-dry, point spread-ase is a suffix used in the names of enzymes. Other words that use the affix -ase include: hyaluronidase, invertase, ligase, lipase, peroxidase
Examples of 'hydroxylase' in a sentence
hydroxylase
Immuno-histochemistry for tyrosine hydroxylase was also performed.
Rafael Campos, Fabíola Z. Mónica, Renata Lopes Rodrigues, Julio Alejandro Rojas-Moscoso,Ronilson Agnaldo Moreno, José Carlos Cogo, Marco Antonio de Oliveira, Edson Antunes,Gilberto De Nucci 2017, 'Tetrodotoxin-insensitive electrical field stimulation-induced contractions on Crotalusdurissus terrificus corpus cavernosum', PLOS ONE10.1371/journal.pone.0183766. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Tyrosine hydroxylase levels were unaltered, suggesting a dysregulation of dopamine activity rather than cell number.
Stephen C Gammie, Michelle N Edelmann, Caleigh Mandel-Brehm, Kimberly L D'Anna, AnthonyP Auger, Sharon A Stevenson 2008, 'Altered dopamine signaling in naturally occurring maternal neglect.', PLoS ONEhttp://europepmc.org/articles/PMC2276864?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Single crosses inherit maternal and paternal alleles of gene of β-carotene hydroxylase codominantly.
Ю. О. Гончаров, Т. М. Сатарова, Б. В. Дзюбецький, В. Ю. Черчель 2016, 'Allelic status of key genes of carotenogenesis on DNA-markers in maize lines and theirhybrids', Plant Varieties Studying and Protectionhttp://journal.sops.gov.ua/article/view/88666. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Expression of extra-renal 1α-hydroxylase was evaluated in endothelial cells of study participants.
Emily S Andrews, Loni Perrenoud, Kristen L Nowak, Zhiying You, Andreas Pasch, MichelChonchol, Jessica Kendrick, Diana Jalal 2018, 'Examining the effects of uric acid-lowering on markers vascular of calcification andCKD-MBD; A post-hoc analysis of a randomized clinical trial.', PLoS ONEhttp://europepmc.org/articles/PMC6200237?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Post mortem analysis included stereological quantification of tyrosine hydroxylase, astrocytes and microglia.
Yu Meixiang, Cooper Oliver, Ferree Andrew, Sánchez-Pernaute Rosario, Brownell Anna-Liisa,Isacson Ole 2004, 'Selective COX-2 inhibition prevents progressive dopamine neuron degeneration in arat model of Parkinson's disease', Journal of Neuroinflammationhttp://www.jneuroinflammation.com/content/1/1/6. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The projecting dopaminergic neurons were identified using tyrosine hydroxylase immunohistochemistry.
Hyoung F Kim, Ali eGhazizadeh, Okihide eHikosaka 2014, 'Separate groups of dopamine neurons innervate caudate head and tail encoding flexibleand stable value memories', Frontiers in Neuroanatomyhttp://journal.frontiersin.org/Journal/10.3389/fnana.2014.00120/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Western blotting was employed to measure changes in hepatic cholesterol 7α hydroxylase protein.
Lindsey R. Boone, Patricia A. Brooks, Melissa I. Niesen, Gene C. Ness 2011, 'Mechanism of Resistance to Dietary Cholesterol', Journal of Lipidshttp://dx.doi.org/10.1155/2011/101242. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The major arcuate dopamine/ tyrosine hydroxylase nerve cell group was found in the dorsomedial part.
W. Romero-Fernandez, D.O. Borroto-Escuela, V. Vargas-Barroso, M. Narváez, M. Di Palma,L.F. Agnati, J. Larriva Sahd, K. Fuxe 2014, 'Dopamine D1 and D2 receptor immunoreactivities in the arcuate-median eminence complexand their link to the tubero-infundibular dopamine neurons', European Journal of Histochemistryhttp://www.ejh.it/index.php/ejh/article/view/2400. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
At 8 weeks post-transplantation, engrafted dopaminergic neurons expressed tyrosine hydroxylase.
Hsu Shan-hui, Cheng Fu-Chou, Su Hong-Lin, Chuang Chieh-Sen, Chuang Chi-Fen, Liu Chin-San 2010, 'Quantitative evaluation of motor function before and after engraftment of dopaminergicneurons in a rat model of Parkinson's disease', Journal of Biomedical Sciencehttp://www.jbiomedsci.com/content/17/1/9. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)