Surprisingly, we also observe the widespread appearance of presynaptically derived "debris" during normal synaptic growth.
Yuly Fuentes-Medel, Mary A Logan, James Ashley, Bulent Ataman, Vivian Budnik, MarcR Freeman 2009, 'Glia and muscle sculpt neuromuscular arbors by engulfing destabilized synaptic boutonsand shed presynaptic debris.', PLoS Biologyhttp://europepmc.org/articles/PMC2724735?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The former, acting presynaptically, may provide a "brake" to prevent vagal overactivity.
Ballal Mansour, Sanford Paul 1999, 'The physiology of the biliary tree. Motility of the gallbladder - Part 1', The Saudi Journal of Gastroenterologyhttp://www.saudijgastro.com/article.asp?issn=1319-3767;year=1999;volume=5;issue=3;spage=93;epage=105;aulast=Ballal. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)