A diagnosis of lymphoplasmacytic lymphoma complicated by blinding hyperviscosity retinopathy was made.
Abdulkabir A. Ayanniyi, Uchenna Godswill Ejikeme, Yohanna Tanko, Rilwan C. Muhammad,Obiageli E. Nnodu 2014, 'Blinding Bilateral Hyperviscosity Retinopathy in a 43-Year-Old Nigerian Male withLymphoplasmacytic Lymphoma: A Case Report and Management Challenges', Case Reports in Oncological Medicinehttp://dx.doi.org/10.1155/2014/567632. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
No manifestation of hyperviscosity syndrome was noted.
Po-Jui Chi, Sung-Nan Pei, Tung-Liang Huang, Shun-Chen Huang, Hwee Yeong Ng, Chien-TeLee 2014, 'Renal MALT lymphoma associated with Waldenström macroglobulinemia', Journal of the Formosan Medical Associationhttp://www.sciencedirect.com/science/article/pii/S0929664612000460. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Neurological complications are common usually as a result of hyperviscosity.
Daniel Halperin, Simon Hallam, Athar Haroon, Tom Butler, Samir Agrawal 2016, 'Bing-Neel Syndrome Case Report: A Previously Undocumented IgG Variant with MRI, PET/CT,and PET/MRI Imaging', Case Reports in Hematologyhttp://dx.doi.org/10.1155/2016/3931709. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The visual function and the hyperviscosity-associated retinopathy were partially restored.
Constantine D. Georgakopoulos, Panagiotis Plotas, Angelos Angelakis, KonstantinosKagkelaris, Evangelia Tzouvara, Olga E. Makri 2019, 'Dexamethasone implant for immunogammopathy maculopathy associated with IgA multiplemyeloma', Therapeutic Advances in Ophthalmologyhttps://doi.org/10.1177/2515841418820441. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Signs of hyperviscosity syndrome become clinically overt at the point of 4 centipoise units.
Boban Marko, Persic Viktor, Pehar-Pejcinovic Vesna, Bursic Vedran, Detanac S. Dzemail 2013, 'Tei index might be the unique echocardiographic parameter that detects hyperviscositysyndrome: A case report', Sanamedhttp://sanamed.rs/sanamed_pdf/sanamed_8_2/TEI_INDEX_MIGHT_BE_THE_UNIQUE_ECHOCARDIOGRAPHIC_PARAMETER_THAT_DETECTS_HYPERVISCOSITY_SYNDROME.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Presentation with symptoms related to hyperviscosity, hypercalcemia and bleeding tendency could also be observed.
Ceyhun Varım, Hasan Ergenc, Mehmet Sevki Uyanık, Tezcan Kaya, Ahmet Nalbant, CengizKaracaer, Cenk Sunu, Ali Tamer 2015, 'A Very Rare Presentation of Multiple Myeloma: Unilateral Raccoon Eye', Open Access Macedonian Journal of Medical Scienceshttp://www.id-press.eu/mjms/article/view/359. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Ophthalmic manifestations include hyperviscosity retinopathy and retinal detachment.
Ari Andayani, I Putu Budhiastra, I Wayan Losen Adnyana, Made Paramita Wijayati 2017, 'Resolution of Retinal Bleeding And Exudative Retinal Detachment After Chemotherapywith Melphalan In Multiple Myeloma', IJRETINA (International Journal of Retina)https://www.ijretina.com/index.php/ijretina/article/view/10. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Workup was negative for cryoglobulins and hyperviscosity syndrome.
Tanawan Riangwiwat, Chris Y. Wu, Alberto S. Santos-Ocampo, Randal J. Liu, Aaron M.McMurtray, Beau K. Nakamoto 2016, 'CNS Vasculitis Associated with Waldenström Macroglobulinemia', Case Reports in Neurological Medicinehttp://dx.doi.org/10.1155/2016/2510573. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
This version could be run without hyperviscosity, as no significant computational noise mode was generated by condensation.
J. Steppeler, J. Li, F. Fang, J. Zhu 2019, 'Test of a cubic spline interface for physical processes with a 1-D third-order spectralelement model', Tellus: Series A, Dynamic Meteorology and Oceanographyhttp://dx.doi.org/10.1080/16000870.2019.1591846. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)