the nonprotein component of a conjugated protein, such as the lipid group in a lipoprotein
prosthetic group in American English
noun
Biochemistry
the nonprotein acid constituent of a conjugate protein, as the heme group of hemoglobin
Word origin
[1895–1900]This word is first recorded in the period 1895–1900. Other words that entered Englishat around the same time include: Marxism, backwind, flamenco, neon, slapstick
Examples of 'prosthetic group' in a sentence
prosthetic group
Cytochromes c are hemoproteins, with the prosthetic group covalently linked to theapoprotein, which function as electron carriers.
Stéphane T. Gabilly, Stéphane T. Gabilly, Patrice P. Hamel, Patrice P. Hamel 2017, 'Maturation of Plastid c-type Cytochromes', Frontiers in Plant Sciencehttp://journal.frontiersin.org/article/10.3389/fpls.2017.01313/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The reduction of ferric iron in the prosthetic group of the protein to the ferrous form was observed.
K. C. S. Figueiredo, T. L. M. Alves, C. P. Borges 2014, 'Myoglobin entrapment in poly(vinyl alcohol) dense membranes', Brazilian Journal of Chemical Engineeringhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-66322014000300017&lng=en&tlng=en. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Heme serves as a prosthetic group for several proteins that constitute the complexes of mitochondrial electron transport chain.
Sarada Preeta Kalainayakan, Keely E. FitzGerald, Purna Chaitanya Konduri, ChantalVidal, Li Zhang 2018, 'Essential roles of mitochondrial and heme function in lung cancer bioenergetics andtumorigenesis', Cell & Biosciencehttp://link.springer.com/article/10.1186/s13578-018-0257-8. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)