Almost all the submucosal tumor-like adenocarcinomas previously reported invaded the submucosa or deeper.
Dobashi Akira, Goda Kenichi, Yoshimura Noboru, Sumiyama Kazuki, Toyoizumi Hirobumi,Saito Shoichi, Kato Tomohiro, Ishikawa Hiroki, Yanaga Katsuhiko, Tajiri Hisao, IkegamiMasahiro 2012, 'Early duodenal adenocarcinoma resembling a submucosal tumor cured with endoscopicresection: a case report', Journal of Medical Case Reportshttp://www.jmedicalcasereports.com/content/6/1/280. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Porcine small intestinal submucosa has been shown to be effective in tissue repair.
Cassiana Maria Garcez Ramos, Julio César Francisco, Marcia Olandoski, Katherine AthaydeTeixeira de Carvalho, Ricardo Cunha, Bruna Olandoski Erbano, Lianna Ferrari Jorge,Cristina Pellegrino Baena, Vivian Ferreira do Amaral, Lucia Noronha, Rafael Michelde Macedo, José Rocha Faria-Neto, Luiz César Guarita-Souza 2014, 'Myocardial regeneration after implantation of porcine small intestinal submucosa inthe left ventricle', Brazilian Journal of Cardiovascular Surgeryhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382014000200202&lng=en&tlng=en. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Despite the tumor being confined within the submucosa, massive lymphatic invasion was noted.
Shoichiro Mukai, Yuji Takakura, Hiroyuki Egi, Takao Hinoi, Yasufumi Saito, Naoki Tanimine,Masashi Miguchi, Tomohiro Adachi, Manabu Shimomura, Hideki Ohdan 2012, 'Submucosal Invasive Micropapillary Carcinoma of the Colon with Massive Lymph NodeMetastases: A Case Report', Case Reports in Oncologyhttp://www.karger.com/Article/FullText/345566. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Edema occurred in the submucosa of the gastrointestinal tract and in body cavities.
Célso Pilati, Claudio S.L. Barros 2007, 'Intoxicação experimental por Senecio brasiliensis (Asteraceae) em eqüinos Experimentalpoisoning by Senecio brasiliensis (Asteraceae) in horses', Pesquisa Veterinária Brasileirahttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2007000700006. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Only one lesion (1.3%) invaded the submucosa.
Carlos Eduardo Oliveira dos SANTOS, Daniele MALAMAN, Tiago dos Santos CARVALHO, CésarVivian LOPES, Júlio Carlos PEREIRA-LIMA 2014, 'MALIGNANCY IN LARGE COLORECTAL LESIONS', Arquivos de Gastroenterologiahttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032014000300235&lng=en&tlng=en. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The esophageal glands were present in submucosa.
H. Zhang, X. Guo, S. Zhong, T. Ge, S. Peng, P. Yu, Z. Zhou 2015, 'Heterogeneous vesicles in mucous epithelial cells of posterior esophagus of Chinesegiant salamander (Andrias davidianus)', European Journal of Histochemistryhttp://www.ejh.it/index.php/ejh/article/view/2521. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Granulomas in the vesical submucosa were observed in 46.2% (12/26) of the individuals.
Iran Mendonça da Silva, Roberto Thiengo, Maria José Conceição, Luis Rey, HenriqueLeonel Lenzi, Edson Pereira Filho, Paulo César Ribeiro 2005, 'Therapeutic failure of praziquantel in the treatment of Schistosoma haematobium infectionin Brazilians returning from Africa', Memórias do Instituto Oswaldo Cruz.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000400018. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The lesion was vaguely nodular and mainly involved the submucosa and proper muscle layer.
Chang Gok Woo, Jeong Hwan Yook, Ah Young Kim, Jihun Kim 2016, 'IgG4-Related Disease Presented as a Mural Mass in the Stomach', Journal of Pathology and Translational Medicinehttp://www.jpatholtm.org/upload/pdf/jptm-2015-07-28.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)