an antibiotic drug of the sulphonamide group, commonly used in combination with pyrimethamine to treat malaria, and in combination with various drugs to treat certain infections
Examples of 'sulphadoxine' in a sentence
sulphadoxine
Volunteers were given sulphadoxine/pyrimethamine 2 wk before the final vaccination.
Vasee S Moorthy, Egeruan B Imoukhuede, Paul Milligan, Kalifa Bojang, Sheila Keating,Pauline Kaye, Margaret Pinder, Sarah C Gilbert, Gijs Walraven, Brian M Greenwood,Adrian S V Hill 2004, 'A randomised, double-blind, controlled vaccine efficacy trial of DNA/MVA ME-TRAP againstmalaria infection in Gambian adults.', PLoS Medicinehttp://europepmc.org/articles/PMC524376?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Tanzania replaced chloroquine with sulphadoxine-pyrimethamine, and in 2006 artemisinin was introduced in the therapy.
Gian Maria Pacifici 2018, 'Treatment of Malaria Parasitaemia in Infants and their Mothers', International Journal of Pediatricshttp://ijp.mums.ac.ir/article_10318_5a16d4076ab4994e3b10a9ef8fdee02d.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Some 20.8% were prescribed combination therapy; the commonest was chloroquine with sulphadoxine-pyrimethamine.
Okebe Joseph, Eke-Njoku John, Oyo-Ita Angela, Nwachukwu Chukwuemeka, Okomo Uduak,Meremikwu Martin, Oyo-Ita Esu, Garner Paul 2007, 'Antimalarial drug prescribing practice in private and public health facilities inSouth-east Nigeria: a descriptive study', Malaria Journalhttp://www.malariajournal.com/content/6/1/55. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Mutant pfdhps isolates also had increased gch1 copy number suggestive that it may also facilitate sulphadoxine resistance.
Musah Osei, Felix Ansah, Sena A. Matrevi, Kwaku P. Asante, Gordon A. Awandare, NeilsB. Quashie, Nancy O. Duah 2018, 'Amplification of GTP-cyclohydrolase 1 gene in Plasmodium falciparum isolates withthe quadruple mutant of dihydrofolate reductase and dihydropteroate synthase genesin Ghana', PLOS ONE10.1371/journal.pone.0204871. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The most commonly used anti-malarials were chloroquine (76%), sulphadoxine-pyrimethamine(9%), herbal preparations (9%) and amodiaquine (6%).
Dodoo Alex NO, Duwiejua Mahama, Buabeng Kwame O, Matowe Lloyd K, Enlund Hannes 2007, 'Self-reported use of anti-malarial drugs and health facility management of malariain Ghana', Malaria Journalhttp://www.malariajournal.com/content/6/1/85. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Only 8.8% of the private pharmacies prescribed artesunate plus sulphadoxine/pyrimethamine, while 53.1% prescribedchloroquine as first-line therapy.
Moonen Bruno, Rage Ismail A, Noor Abdisalan M, Snow Robert W 2009, 'Health service providers in Somalia: their readiness to provide malaria case-management',Malaria Journalhttp://www.malariajournal.com/content/8/1/100. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Here, we report oral artesunate, sulphadoxine and pyrimethamine (sp) induced cardio toxicity case in a female patient.
Divya Goel, Shafiqa Aslam, Rani Walia, Akshay Sadhotra 2016, 'Artesunate-, sulfadoxine-, and pyrimethamine-induced cardiotoxicity', BLDE University Journal of Health Scienceshttp://www.bldeujournalhs.in/article.asp?issn=2468-838X;year=2016;volume=1;issue=1;spage=54;epage=56;aulast=Goel. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)