of similar origin, as parts derived from the same embryonic tissue
2. Also: isogenic (ˌaɪsəʊˈdʒɛnɪk)
genetically uniform
Derived forms
isogeny (iˈsogeny)
noun
Examples of 'isogenic' in a sentence
isogenic
Genes encoding manno-heptose synthetases or glycosyltransferases were inactivated to generate isogenic mutants.
Taketoshi Iwata, Kazuhiro Chiku, Ken-ichi Amano, Masahiro Kusumoto, Mayumi Ohnishi-Kameyama,Hiroshi Ono, Masato Akiba 2013, 'Effects of Lipooligosaccharide Inner Core Truncation on Bile Resistance and ChickColonization by Campylobacter jejuni', PLoS ONE10.1371/journal.pone.0056900. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Isogenic strains were sequenced to identify the mutation related to a small colony size.
Hirotsugu Banno, Kouji Kimura, Yosuke Tanaka, Tsuyoshi Sekizuka, Makoto Kuroda, WanchunJin, Jun-ichi Wachino, Keiko Yamada, Keigo Shibayama, Yoshichika Arakawa 2017, 'Analysis of multidrug resistant group B streptococci with reduced penicillin susceptibilityforming small, less hemolytic colonies', PLOS ONE10.1371/journal.pone.0183453. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Flow cytometry using convalescent serum detected a variable surface recognition signal on isogenic clonal parasites.
Ellen Inga Bruske, Sandra Dimonte, Corinna Enderes, Serena Tschan, Matthias Flötenmeyer,Iris Koch, Jürgen Berger, Peter Kremsner, Matthias Frank 2016, 'In Vitro Variant Surface Antigen Expression in Plasmodium falciparum Parasites froma Semi-Immune Individual Is Not Correlated with Var Gene Transcription', PLOS ONE10.1371/journal.pone.0166135. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Cellular heterogeneity greatly determines the fraction of oscillating cells among a population of isogenic cells.
Dao-Guang Wang, Shaobing Wang, Bo Huang, Feng Liu 2019, 'Roles of cellular heterogeneity, intrinsic and extrinsic noise in variability of p53oscillation', Scientific Reportshttp://link.springer.com/article/10.1038/s41598-019-41904-9. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Virus-cured isogenic strains did not show significant changes in colony morphology.
Jeesun Chun, Han-Eul Yang, Dae-Hyuk Kim 2018, 'Identification and Molecular Characterization of a Novel Partitivirus from Trichodermaatroviride NFCF394', Viruseshttps://www.mdpi.com/1999-4915/10/11/578. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We have compared a defined wild-type strain with its isogenic strains lacking well-characterized virulence factors.
Jonas eGripenland, Christopher eAndersson, Jörgen eJohansson 2014, 'Exploring the chicken embryo as a possible model for studying Listeria monocytogenespathogenicity', Frontiers in Cellular and Infection Microbiologyhttp://journal.frontiersin.org/Journal/10.3389/fcimb.2014.00170/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Isogenic populations of animals still show a surprisingly large amount of phenotypic variation between individuals.
Alexander K Seewald, James Cypser, Alexander Mendenhall, Thomas Johnson 2010, 'Quantifying phenotypic variation in isogenic Caenorhabditis elegans expressing Phsp-16.2::gfpby clustering 2D expression patterns.', PLoS ONEhttp://europepmc.org/articles/PMC2906502?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Three isogenic rainbow trout lines were used for evaluating possible family effects.
Inge Geurden, Peter Borchert, Mukundh N Balasubramanian, Johan W Schrama, MathildeDupont-Nivet, Edwige Quillet, Sadasivam J Kaushik, Stéphane Panserat, Françoise Médale 2013, 'The positive impact of the early-feeding of a plant-based diet on its future acceptanceand utilisation in rainbow trout.', PLoS ONEhttp://europepmc.org/articles/PMC3873907?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Isogenic bacteria can exhibit a range of phenotypes, even in homogeneous environmental conditions.
Sivan Pearl, Chana Gabay, Roy Kishony, Amos Oppenheim, Nathalie Q Balaban 2008, 'Nongenetic individuality in the host-phage interaction.', PLoS Biologyhttp://europepmc.org/articles/PMC2386839?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Furthermore, we generate near-isogenic strains to directly demonstrate that two of these loci influence resistance.
Keir M Balla, Erik C Andersen, Leonid Kruglyak, Emily R Troemel 2015, 'A wild C. elegans strain has enhanced epithelial immunity to a natural microsporidianparasite.', PLoS Pathogenshttp://europepmc.org/articles/PMC4334554?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)