any of a group of synthetic antibiotics, including ciprofloxacin, that inactivate an enzyme required for the replication of certain microorganisms
Examples of 'quinolone' in a sentence
quinolone
On a skin infection suspicion, treatment with quinolone and neomycin sulfate was initiated, without improvement.
Giovana Memari Pavanelli, Sibele Sauzem Milano, Gabriela Sevignani, Juliana ElizabethJung, Vaneuza Araujo Moreira Funke, Marcelo Mazza do Nascimento 2018, 'Furosemide-induced pseudoporphyria in a patient with chronic kidney disease: casereport', Brazilian Journal of Nephrologyhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002018005020102&lng=en&tlng=en. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Quinolone resistance was significantly associated with extended- spectrum beta-lactamase-production (p=0.0001).
Elif ŞAHİN HORASAN, Gülden ERSÖZ, Mustafa UĞUZ, Gürol EMEKDAŞ, Ali KAYA 2010, 'Antimicrobial Resistances of Escherichia coli Isolates Causing Bacteremia (2004-2009)',Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisihttp://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2010-15-4-147-152.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
All isolates showing nonclassical quinolone resistance were from travelers to these 2 countries.
Marianne M. Lindgren, Pirkko Kotilainen, Pentti Huovinen, Saija Hurme, Susanna Lukinmaa,Mark A. Webber, Laura J.V. Piddock, Anja Siitonen, Antti J. Hakanen 2009, 'Reduced Fluoroquinolone Susceptibility in Salmonella enterica Isolates from Travelers,Finland', Emerging Infectious Diseaseshttps://wwwnc.cdc.gov/eid/article/15/5/08-0849_article. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
He denied having taken any other antibiotics, especially no quinolone antibiotics.
Patric Scheidegger, Lukas Weisskopf, Anja Hirschmüller 2017, 'Atraumatic bilateral rupture of the peroneus brevis tendon in recreational sport:A case report', SAGE Open Medical Case Reportshttps://doi.org/10.1177/2050313X17745225. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Quinolone antibiotics exert their pharmacological effect by inhibiting the cell wall synthesis of the pathogen.
E. MANOGRAN, M. ASHRAF ALI, A. AHAMED SIDDIQUI, M. SHAHAR YAR 2006, 'Design of targeted dosage form of ofloxacin', Journal of the Serbian Chemical Societyhttp://www.shd.org.yu/HtDocs/SHD/Vol71/No12/JSCS_V71_No12-03.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Types possessing macrolide- and quinolone-resistance genes were 18.4% and 2.6%, respectively; none showed β-lactam resistance.
Takeaki Wajima, Miyuki Morozumi, Shigeo Hanada, Katsuhiko Sunaoshi, Naoko Chiba, SatoshiIwata, Kimiko Ubukata 2016, 'Molecular Characterization of Invasive Streptococcus dysgalactiae subsp. equisimilis,Japan', Emerging Infectious Diseaseshttps://wwwnc.cdc.gov/eid/article/22/2/14-1732_article. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We anticipate that these findings may be useful for the design of quinolone treatments.
Elizabeth L. Sandvik, Christopher H. Fazen, Theresa C. Henry, Wendy W.K. Mok, MarkP. Brynildsen 2015, 'Non-Monotonic Survival of Staphylococcus aureus with Respect to Ciprofloxacin ConcentrationArises from Prophage-Dependent Killing of Persisters', Pharmaceuticalshttp://www.mdpi.com/1424-8247/8/4/778. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Associated quinolone resistance was found in 46.2% of these isolates.
Hagen Frickmann, Dorothea Wiemer, Claudia Frey, Ralf Matthias Hagen, Rebecca Hinz,Andreas Podbielski, Thomas Köller, Philipp Warnke 2016, 'Low Enteric Colonization with Multidrug-Resistant Pathogens in Soldiers Returningfrom Deployments- Experience from the Years 2007-2015.', PLoS ONEhttp://europepmc.org/articles/PMC5012679?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Overall, 5/9 (56%) patients with septicaemia were quinolone resistant.
Rustom P. Manecksha, Gregory J. Nason, Ivor M. Cullen, Jérôme P. Fennell, ElizabethMcEvoy, Ted McDermott, Robert J. Flynn, Ronald Grainger, John A. Thornhill 2012, 'Prospective Study of Antibiotic Prophylaxis for Prostate Biopsy Involving >1100 Men',The Scientific World Journalhttp://dx.doi.org/10.1100/2012/650858. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The presence of quinolone-resistant strains was 34% at a local level and 26% in hospitals.
Stefano Picozzi, Cristian Ricci, Maddalena Gaeta, Alberto Macchi, Emmanuel Dinang,Gaia Paola, Milvana Tejada, Elena Costa, Giorgio Bozzini, Stefano Casellato, LucaCarmignani 2013, 'Do we really know the prevalence of multi-drug resistant Escherichia coli in the territorialand nosocomial population?', Urology Annalshttp://www.urologyannals.com/article.asp?issn=0974-7796;year=2013;volume=5;issue=1;spage=25;epage=29;aulast=Picozzi. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)