a ruined village in E Virginia, on Jamestown Island (a peninsula in the James River): the first permanent settlement by the English in America (1607); capital of Virginia (1607–98); abandoned in 1699
Jamestown in American English
(ˈdʒeɪmzˌtaʊn)
1.
former village near the mouth of the James River, Va.: the 1st permanent English colonial settlement in America (1607)