a type of diabetes medicine taken orally to slow and reduce the supply of glucose to the blood.
Examples of 'acarbose' in a sentence
acarbose
Therefore, the exact mechanisms by which acarbose affects glucose metabolism are unclear.
Qian Zhang, Xinhua Xiao, Ming Li, Wenhui Li, Miao Yu, Huabing Zhang, Zhixin Wang,Hongding Xiang 2013, 'Acarbose Reduces Blood Glucose by Activating miR-10a-5p and miR-664 in Diabetic Rats',PLoS ONE10.1371/journal.pone.0079697. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Acarbose was used as an alternative strategy.
Cárdenas-Elizalde MR, Kravzov-Jinich J, Altagracia-MartínezM, Díaz de León-Castañeda C, Martínez-NúñezJM, Moreno-Bonett C 2012, 'Cost-effectiveness study of oral hypoglycemic agents in the treatment of outpatientswith type 2 diabetes attending a public primary care clinic in Mexico City', ClinicoEconomics and Outcomes Researchhttp://www.dovepress.com/cost-effectiveness-study-of-oral-hypoglycemic-agents-in-the-treatment--a9433. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The effects were comparable to those of acarbose (5 mg/kg).
Sonia Escandón-Rivera, Araceli Pérez-Vásquez, Andrés Navarrete, Mariana Hernández,Edelmira Linares, Robert Bye, Rachel Mata 2017, 'Anti-Hyperglycemic Activity of Major Compounds from Calea ternifolia', Moleculeshttp://www.mdpi.com/1420-3049/22/2/289. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Acarbose was used as the standard inhibitor.
Mahsa Rahimzadeh, Samaneh Jahanshahi, Soheila Moein, Mahmood Reza Moein 2014, 'Evaluation of alpha- amylase inhibition by Urtica dioica and Juglans regia extracts',Iranian Journal of Basic Medical Scienceshttp://ijbms.mums.ac.ir/pdf_2933_a2a6170dfb40c196c4d864c01c7ebd59.html. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Additionally, dissolved oxygen has a great effect on acarbose production based on model predictions.
Yali eWang, Yali eWang, Yali eWang, Nan eXu, Nan eXu, Chao eYe, Chao eYe, Liming eLiu,Liming eLiu, Zhongping eShi, Zhongping eShi, Jing eWu, Jing eWu 2015, 'Reconstruction and in silico analysis of an Actinoplanes sp. SE50/110 genome-scalemetabolic model for acarbose production', Frontiers in Microbiologyhttp://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00632/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
All the extracts have shown mild α-amylase inhibitory activity compared to acarbose.
Manjur Ali Sheliya, Rayhana Begum, Kolappa Krishna Pillai, Vidhu Aeri, Showkat RasoolMir, Abuzer Ali, Manju Sharma 2016, 'In vitro α-glucosidase and α-amylase inhibition by aqueous, hydroalcoholic, and alcoholicextract of Euphorbia hirta L.', Drug Development and Therapeuticshttp://www.ddtjournal.org/article.asp?issn=2394-6555;year=2016;volume=7;issue=1;spage=26;epage=30;aulast=Sheliya. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
All berry extracts showed higher inhibition against α-amylase and α-glucosidase than the anti-diabetic agent acarbose.
Giang Thanh Thi Ho, Thi Kim Yen Nguyen, Eili Tranheim Kase, Margey Tadesse, HildeBarsett, Helle Wangensteen 2017, 'Enhanced Glucose Uptake in Human Liver Cells and Inhibition of Carbohydrate HydrolyzingEnzymes by Nordic Berry Extracts', Moleculeshttps://www.mdpi.com/1420-3049/22/10/1806. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We found that 8-week treatment with acarbose significantly decreased fasting blood glucose.
Qian Zhang, Xinhua Xiao, Ming Li, Wenhui Li, Miao Yu, Huabing Zhang, Zhixin Wang,Hongding Xiang 2013, 'Acarbose Reduces Blood Glucose by Activating miR-10a-5p and miR-664 in Diabetic Rats',PLoS ONE10.1371/journal.pone.0079697. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
However, there was no obvious improvement in cognitive function in the acarbose-donepezil group.
Yufeng Lin, Yufeng Lin, Kaiyuan Wang, Chunchao Ma, Xuesong Wang, Zhongying Gong, RuiZhang, Dawei Zang, Yan Cheng 2018, 'Evaluation of Metformin on Cognitive Improvement in Patients With Non-dementia VascularCognitive Impairment and Abnormal Glucose Metabolism', Frontiers in Aging Neurosciencehttps://www.frontiersin.org/article/10.3389/fnagi.2018.00227/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The treated group received acarbose orally and insulin by subcutaneous injection.
Antonio Carlos Lottelli Rodrigues, Silvana Artioli Schellini, César Tadeu Spadela,Elisa Aparecida Gregório, Carlos Roberto Padovani 2007, 'Alterações vasculares na coróide de ratos diabéticos tratados e não tratados Choroidalvessels alterations in treated and untreated diabetic rats', Arquivos Brasileiros de Oftalmologiahttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492007000300009. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)