The synthesis of boronic thioaminoacids was carried out by free radical thiilation of dialkyl-vinylboronates.
V.M. Dembitsky, G.A. Tolstikov, M. Srebnik 2002, 'Boranes in Organic Chemistry 2. ОІ-Aminoalkyl- and ОІ-Sulfanylalkylboranes in OrganicSynthesis', Eurasian Chemico-Technological Journal http://ect-journal.kz/index.php/ectj/article/view/296. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Three different concentrations of boronic acid were also tested: 300, 400 and 600 µg.
Claudia Michele de Araujo Borba, Viviane Matoso de Oliveira, Lavínia N. V. S. Arend,Marcelo Pilonetto 2012, 'Validação do teste de inibição pelo ácido aminofenilborônico para triagem de Klebsiellapneumoniae carbapenemases (KPC) Validation of inhibition test by aminophenyl boronicacid to Klebsiella pneumoniae carbapenemases (KPC) screening', Jornal Brasileiro de Patologia e Medicina Laboratorialhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442012000600007. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Samples were digested with trypsin and enriched for glycated peptides using boronic acid affinity chromatography.
Sandro Spiller, Yichao Li, Matthias Blüher, Lonnie Welch, Ralf Hoffmann 2017, 'Glycated lysine-141 in haptoglobin improves the diagnostic accuracy for type 2 diabetesmellitus in combination with glycated hemoglobin HbA1c and fasting plasma glucose',Clinical Proteomicshttp://link.springer.com/article/10.1186/s12014-017-9145-1. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Screen test using ertapenem and the boronic acid disk was positive in 14 isolates.
Poothakuzhiyil Remya, Mariappan Shanthi, Uma Sekar 2018, 'Prevalence of blaKPC and its occurrence with other beta-lactamases in Klebsiella pneumoniae',Journal of Laboratory Physicianshttp://www.jlponline.org/article.asp?issn=0974-2727;year=2018;volume=10;issue=4;spage=387;epage=391;aulast=Remya. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Cross-coupling reactions with aromatic and heteroaromatic boronic acids have been investigated.
Clément Ghiazza, Anis Tlili, Thierry Billard 2017, 'Electrophilic Trifluoromethylselenolation of Boronic Acids', Moleculeshttp://www.mdpi.com/1420-3049/22/5/833. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In order to develop colorimetric sugar sensors, boronic acid-conjugated azobenzenes have been synthesized.
Yuya Egawa, Ryotaro Miki, Toshinobu Seki 2014, 'Colorimetric Sugar Sensing Using Boronic Acid-Substituted Azobenzenes', Materialshttp://www.mdpi.com/1996-1944/7/2/1201. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
However, deboronation or isomerization side reactions may occur for several boronicacids.
Clémence Tabélé, Christophe Curti, Youssef Kabri, Nicolas Primas, Patrice Vanelle 2015, 'Cross-Coupling Synthesis of Methylallyl Alkenes: Scope Extension and Mechanistic Study',Moleculeshttp://www.mdpi.com/1420-3049/20/12/19886. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Nuclear magnetic resonance can differentiate between regioisomeric boronic esters and identifies preferred sites of esterification on the dimeric template 9.
Sebastian Nils Fischer, Armin Geyer 2015, 'Assembly of synthetic Aβ miniamyloids on polyol templates', Beilstein Journal of Organic Chemistryhttps://doi.org/10.3762/bjoc.11.284. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Boration of 4,8-dimethoxy-2-quinolone with trimethylborates leading to 2-quinolone-3-boronicacid was described.
V.M. Dembitsky, G.A. Tolstikov, M. Srebnik 2002, 'Boranes in Organic Chemistry 1. О±-Carbonylalkyl- and ОІ-Oxyalkylboranes in OrganicSynthesis', Eurasian Chemico-Technological Journal http://ect-journal.kz/index.php/ectj/article/view/279. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)