a nucleotide which contains ribose as its sugar component
ribonucleotide in American English
(ˌraɪboʊˈnukliəˌtaɪd; ˌraɪboʊˈnjukliəˌtaɪd)
noun
any of various nucleotides in which the carbohydrate component is ribose: a structural unit of RNA
ribonucleotide in American English
(ˌraibouˈnuːkliəˌtaid, -ˈnjuː-)
noun
Biochemistry
an ester, composed of a ribonucleoside and phosphoric acid, that is a constituent of ribonucleic acid
Word origin
[1925–30; ribo(nucleicacid) + nucleotide]This word is first recorded in the period 1925–30. Other words that entered Englishat around the same time include: buildup, chain reaction, dropout, payload, reflex camera
Examples of 'ribonucleotide' in a sentence
ribonucleotide
Ribonucleotide reductase catalyzes the conversion of ribonucleotide diphosphates to deoxyribonucleotide diphosphates.
Vei Mah, Mohammad Alavi, Diana C Márquez-Garbán, Erin L Maresh, Sara R Kim, SteveHorvath, Lora Bagryanova, Sara Huerta-Yepez, David Chia, Richard Pietras, Lee Goodglick 2015, 'Ribonucleotide reductase subunit M2 predicts survival in subgroups of patients withnon-small cell lung carcinoma: effects of gender and smoking status.', PLoS ONEhttp://europepmc.org/articles/PMC4441434?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The synergistic effect was paralleled by a reduced expression of ribonucleotide reductase,potentially facilitating gemcitabine cytotoxicity.
Daniela Massihnia, Amir Avan, Niccola Funel, Mina Maftouh, Anne van Krieken, CarlottaGranchi, Rajiv Raktoe, Ugo Boggi, Babette Aicher, Filippo Minutolo, Antonio Russo,Leticia G. Leon, Godefridus J. Peters, Elisa Giovannetti 2017, 'Phospho-Akt overexpression is prognostic and can be used to tailor the synergisticinteraction of Akt inhibitors with gemcitabine in pancreatic cancer', Journal of Hematology & Oncologyhttp://link.springer.com/article/10.1186/s13045-016-0371-1. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Consistently, the protein expression and enzyme activity of ribonucleotide reductase were also increased in the cervical cancer tissues.
Jin G, Zhao J, Qi H, Lou M, Liu X, Qu Y, Zhao L, Zhang W, Shao J, Zhong H 2013, 'Gemcitabine and carboplatin demonstrate synergistic cytotoxicity in cervical cancercells by inhibiting DNA synthesis and increasing cell apoptosis', OncoTargets and Therapyhttp://www.dovepress.com/gemcitabine-and-carboplatin-demonstrate-synergistic-cytotoxicity-in-ce-a15076. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)